3. Vascular Disease Flashcards

1
Q

Three divisions of peripheral vascular disease?

A

Acute limb ischaemia - sudden decrease in limb perfusion
Critical limb ischaemia - pain at rest
Intermittent ischaemia - pain on exertion

All start as atherosclerosis causing stenosis

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2
Q

Symptoms of acute limb ischaemia?

A
Pain
Pale
Pulseless
Paralysis
Parasthesia
Perishingly cold
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3
Q

Symptoms of critical limb ischaemia and claudication?

A
Hair loss
Numbness
Brittle, slow growing toe nails
Absent pulses
Ulcers
Atrophic skin 

Often asymptomatic - remember claudication is only on movement

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4
Q

What is beurger’s test?

A

Raise foot 45 degree, leg should stay same colour.
If develops pallor then PVD suspected.

less than 20 degrees is severe limb ischaemia.

If you swing the leg back down and it goes red, this is hyperemia.

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5
Q

Vascular disease investigation?

A
  1. Cardio exam - BP, HR, bloods, ECG
  2. Ankle brachial pressure index - gold diagnostic - take bp in arm and leg and divided leg by arm, it should be 0.9-1.2. if lower, abnormal. <0.5 is chronic
  3. Colour duplex USS
  4. Magnetic resonance angiogram
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6
Q

Three types of ulcers?

A

Arterial
Venous
Neuropathic

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7
Q

Arterial ulcer symptoms?

A
Punched out appearance, deep
Distal
Well defined
Pale base - grey
Hair loss, shiny and pale skin around
Calf muscle wasting - no blood supply
Absent pulses
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8
Q

Venous ulcer signs?

A

Large shallow, sloping and poorly defined
More proximal
Swelling, itching or aching
May be associated with - stasis eczema, lipodermatosclerosis (upside down champagne bottle), atrophie blanche (area of white, atrophied skin), hemosiderin depositation (darkened areas)

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9
Q

Investigating arterial and venous ulcers?

A

Duplex USS of lower limbs.
ABPI

Venous - swab for micro, biopsy
Arterial - ECG, perc angio, bloods.

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10
Q

How to manage venous ulcers?

A

Compression stockings
Debridement and cleaning
Antibiotics if infected
Moisturising

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11
Q

What is a true and false aneurysm?

A

True - where all three layers of blood vessels are incorporated
False - only one layer, creates a pouch

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12
Q

Unruptured AAA symptoms?

A

Asymptomatic
Often incidentally
Pulsatile, laterally expansile mass
Abdo bruit

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13
Q

Ruptured AAA symptoms?

A
Sudden, severe pain in back, groin or abdo
Syncope
Shock
Pulsatile, laterally expansile mass
Abdo bruit
Grey-Tuner's sign (bruising on flanks)
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14
Q

AAA investigations?

A

Bloods (incl. cross match)
Abdominal ultrasound (gold standard) to detect pressure and see how wide (wider than 3cm)
CT angiogram to see if rupture (gold for rupture)
Magnetic angiogram if renal impairment.

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15
Q

Diff of aortic dissection?

A
Type A (most common) always incldudes ascending aorta - type 1 - before and after aortic arch
type 2 - is only ascending aorta
Type B - Type 3, only descending aorta

Aortic dissection (false aneurysm that is above the diaphragm)

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16
Q

Aortic dissection symptoms and signs?

A
Tearing pain down chest and radiating to back
Blackout and dysphagia - from carotid
Angina - coronary
Loss of consciousness - subclavian
Renal failure - renal artery
HTN
BP difference between arch of more than 50%
Murmur heard on back
Signs of aortic regurg
OR 
Signs of connective tissue disorder
17
Q

Aortic dissection investigation?

A

Bloods (risk factors)
ECG (causes)
CXR (aortic knuckle, widened mediastinum, globular heart)
CT angiogram (gold standard)

18
Q

What are varicose veins?

A

Subcutaneous, permanently dilated veins more than 3mm in diameter standing.

19
Q

Causes of varicose veins?

A
Primary - idiopathic
Secondary - 
1. Venous outflow obstruction - pregnancy, ascites, pelvic malignancy, ovarian insufficiency (??)
DVT
AV malformation
20
Q

Varicose veins symptoms?

A

Visible dilation
Leg itching with prolonged standing
Swelling and itching
Bleeding

21
Q

Signs of varicose veins?

A

Veins feel tender or hard
Tap test - tap distally and feel thrill at sapheno-femoral junction
Auscultation for bruits
Trendelenburg test (tourniquet above knee whilst leg in air, rapid filling when taking off)

22
Q

Investigations for varicose veins?

A
Duplex USS (gold standard)
DVT assessment
23
Q

Manage varicose veins?

A
Compression stockings
Lifestyle changes
Radiofrequency ablation
Endovenous laser ablation
Microinjection sclerotherapy
Stripping long saphenous vein
Saphenofemoral ligation
Avulsion of varicosities
24
Q

What is gangrene?

A

Tissue necrosis causes by ischaemia, infarction or trauma

25
Q

Types of gangrene?

A

Wet - tissue become pus-y
Dry
Gas - bubbles of gas beneath skin

26
Q

DVT Symptoms?

A
Erythema
Warmth
Swollen limb
Varicosities
Painless
Homan's sign, dorsiflex causes deep pain
Check for a PE (Well's criteria)
27
Q

DVT investigations?

A

Doppler USS (gold standard)
Impedence phlethysmography
D-dimer - strong negative predictive value (if negative, almost certainly unlikely)

28
Q

DVT treatment?

A

DOACs
LMWH
Compression stockings and exercise for prevention