3 - Substance Exchange Flashcards
When does the need for a specialized exchange surface arise?
As the size of an organism, and its SA:V ratio increases
What is required for an efficient exchange surface?
Large SA
Thin
Good blood supply / Ventilation
Fish membrane
Impermeable - gases can’t diffuse through skin
How many pairs of gills do bony fish have?
4 Pairs
What supports each fish gill?
An arch
What is located across each arc supporting fish gills?
Multiple projections called gill filaments, with lamallae on them which participate in gas exchange
How do blood and water flow across the lamellae?
In a counter-current
Benefit of counter-current exchange system in fish
Maintains a steep concentration gradient so the maximum amount of oxygen is diffusing into the deoxygenated blood from the water
How are projections held apart?
By water flow
This means they stick together in the absence of water and the fish cannot survive
What is required to maintain a continuous unidirectional flow in fish?
Ventilation
How does ventilation begin in fish?
Fish opens its mouth, followed by lowering the floor of buccal cavity
Effect of lowering the floor of buccal cavity
Enable water to flow in
What happens after water flows in, in fish ventilation?
The fish closes its mouth, causing the buccal cavity floor to raise, increasing the pressure
What causes the water to be forced over the gill filaments in fish ventilation?
The difference in pressure between the mouth cavity and opercular cavity
Role of operculum in fish ventilation
Acts as a valveand pump and lets water out and pumps it in
How is oxygen obtained in insects?
Oxygen needs to be transported directly to tissues undergoing respiration
Spiracles
Small openings of tubes along the thorax and abdomen
Trachea / tracheoles
Network of small tubes that carry oxygen around the insect body
How is oxygen transported directly into respiring tissues in insects?
With the help of spiracles and either bigger trachea or smaller tracheoles
Gases move in and out through diffusion
What is mass transport in insects a result of?
Muscle contraction and volume changes in the tracheoles
Stomata
Small holes in leaves which allow gases to enter and leave
Purpose of air spaces in leaves
Allows gases to move around the leaf and easily come into contact with photosynthesising mesophyll cells
The Lungs
A pair of lobed structures with a large surface area located in the chest cavity that are able to inflate
Rib Cage
Surrounds the lungs to protect them
How is friction between the lungs and ribs prevented?
Secretion of a lubricating substance
Diaphragm
Separates the lungs from the abdomen area
What contracts to raise and lower the ribcage respectively?
External and internal intercostal muscles
How does air enter humans?
Through the nose, along the trachea, bronchi and bronchioles
Where does gaseous exchange take place in humans?
Alveoli - tiny sacs filled with air
What structures allow the flow of air into and out of the lungs?
Trachea, bronchi and bronchioles
How are human airways held open?
Rings of cartilage, which are incomplete in the trachea to allow the passage of food down the oesophagus behind the trachea
Wall of trachea and bronchi
Composed of several layers which together make a thick wall
The wall is mostly composed of cartilage, in the form of incomplete C rings
Inside surface of Cartilage of trachea and bronchi
Layer of loose tissue
Inner lining of Cartilage of trachea and bronchi
Epithelial layer composed of ciliated epithelium and goblet cells
What are bronchiole walls made of?
Smooth muscle and elastic fibre
How are the alveoli adapted for transport?
1 cell thick - surrounded by capillaries which are also 1 cell thick - reduces diffusion distance
Constant blood supply by capillaries maintains a steep concentration gradient
Large number of alveoli - Increase SA
Role of Cartilage in gas exchange
Supporting the trachea and bronchi
Plays an important role in preventing the lungs from collapsing in the event of pressure drop during excitation
Ciliated Epithelium in gas exchange
Present in bronchi, bronchioles and trachea
Moving mucus along to prevent lung infection by moving it towards the throat where it can be swallowed
Goblet cells in gas exchange
Present in trachea, bronchi and bronchioles
Involved in mucus production to trap bacteria and dust to reduce the risk of infection with the help of lysozymes which digest bacteria
Smooth Muscle in gas exchange
Their ability to contract enables them to play a role in constricting the airway
Controlling diameter which controls the flow of air from the alveoli
Elastic fibres in gas exchange
Stretch when we exhale and recoil when we inhale, thus controlling flow of air
2 stages of ventilation
Inspiration
Expiration
Inspiration
External intercostal muscles contract
Internal muscles relax
Ribs raise upwards
Diaphragm contracts and flattens
Effect of intercostal muscles and diaphragm in inspiration
Cause the volume inside the thorax to increase, lowering the pressure
The difference between the pressure inside the lungs and atmospheric pressure creates a gradient, causing air to be forced into the lungs
Expiration
Internal intercostal muscles contract
External muscles relax, lowering rib cage
Diaphragm relaxes and raises upwards
Decreases the volume in the thorax, forcing air out of the lungs
Spirometer
Used to measure lung volume
Vital Capacity
The max volume of air that can be inhaled or exhaled in a single breath
Tidal Volume
The volume of air we breathe in and out at each breath at rest
How can breathing rate be calculated from the spirometer?
Counting the number of peaks in a minute
Residual Volume
Volume of air always present in lungs
Expiratory reserve volume
Additional volume of air that can be exhaled on top of the tidal volume
Digestion
The hydrolysis of large biological molecules into smaller molecules which can be absorbed across cell membranes
Amylase
In the mouth, digests larger Carbohydrate polymers
Maltase
In the ileum, break down monosaccharides
Sucrase and lactases
Break down the disaccharides sucrose and lactose respectively
How are lipids digested?
Lipases hydrolyses the ester bond between the monoglyceride and fatty acid
What happens before lipids are broken down in the ileum?
Lipids are emulsified into micelles by bile salts released from the liver
Where are lipids broken down?
Ileum
How are lipids emulsified into micelles?
By bile salts released by the liver
Effect of emulsification of lipids
Increases the SA and speeds up the chemical reaction
Endopeptidases
Hydrolyses peptide bonds between specific amino acids in the middle of the polypeptide
Exopeptidases
Hydrolyses bonds at the ends of a polypeptide
Dipeptidase
Hydrolyses dipeptides into individual amino acids
What happens to products of digestion?
Absorbed by cells lining the ileum of mammals
How are amino acids absorbed?
Facilitated diffusion through specific carrier molecules in the surface membrane of epithelial cells
Why can monoglyceride and fatty acids easily diffuse across the cell membrane?
They are polar
Advantage of monoglyceride and fatty acids being polar
Easily diffuse across the cell membrane into the eithelial cells lining the epithelium
What happens once monoglyceride and fatty acids are inside the cell?
They are transported to the endoplasmic reticulum where they are reformed into triglycerides.
What happens once monoglycerides and fatty acids have been reformed into triglycerides by the endoplasmic reticulum?
They move out of the cells by vesicles in the lymph system
Haemoglobin
Water soluble globular protein, Consisting of 2 beta polypeptide chains and 2 alpha helices
What does each molecule in haemoglobin molecule form?
A complex containing a haem group
How does haemoglobin carry oxygen in the blood?
Oxygen can bind to the haem group
Each molecule can carry 4 oxygen molecules
What does the affinity of oxygen for haemoglobin depend on?
Partial pressure of oxygen
What happens as partial pressure of oxygen increases?
The affinity of haemoglobin for oxygen increases
Effect of respiration on affinity of oxygen for haemoglobin
During respiration, oxygen is used up and therefore the partial pressure decreases, decreasing the affinity of oxygen for haemoglobin
Loading
Oxygen binds tightly to haemoglobin
Result of decreased affinity of oxygen for haemoglobin
Oxygen is released in respiring tissues where it is needed
What happens after the unloading process of oxygen>
Haemoglobin returns to the lungs where it binds to oxygen again
Why does fetal haemoglobin have a greater affinity for oxygen?
It needs to be better as absorbing oxygen as by the time oxygen reaches the placenta, the oxygen saturation of the blood has decreased
How is fetal haemoglobin different from adult haemoglobin?
It has a higher affinity for oxygen in order for the foetus to survive at low partial pressure
Effect of CO2 on haemoglobin affinity for oxygen
Presence of CO2 decreases the haemoglobin affinity for oxygen, causing it to be released
Bohr effect
Presence of CO2 decreasing the affinity of haemoglobin for oxygen, causing it to be released
How does CO2 cause oxygen to be released from haemoglobin?
CO2 creates slightly acidic conditions which change the shape of the haemoglobin protein, making it easier for the oxygen to be released
Why is a circulatory system needed in large organisms?
The SA:V is not large enough to for difussion alone to supply substances like oxygen, glucose and other molecules to cells where they are needed
Common Features of a circulatory system
Suitable medium
Means of moving medium
Mechanism to control flow around the body
Close system of vessels
Suitable transport medium in mammals
In mammals the transport medium is the blood
It is water based so substances can easily dissolve into it
Means of moving the medium (blood) in mammals
Animals often have a pump known as the heart to maintain pressure differences around the body
Mechanism to control flow around the body
Valves are used in veins to prevent any backflow
Close system of vessels
The circulatory system in most animals and plants is closed and is branched to deliver substances to all parts of the body
Circulatory system in mammals
Closed double circulatory system
2 Pumps of the heart
One pumps blood to the lungs to be oxygenates
The other is larger and stronger and pumps the oxygenated blood around the body to supply vital organs and tissues
Atrium - Features
Thin walled and elastic
Can stretch when filed with blood
Ventricle
Thick muscular wall to pump blood around the body or to the lungs
Why are 2 Pumps required in the heart?
Maintain blood pressure around the whole body
Why would just 1 pump in the heart not be able to maintain blood pressure around the whole body?
The slow down of blood as it passes the lungs would cause it to lose all pressure
4 main vessels connecting the heart
Aorta
Pulmonary artery
Pulmonary vein
Vena cava
Aorta - role
Connected to the left ventricle and carries oxygenated blood to all parts of the body, except the lungs
Pulmonary artery
Connected to the right ventricle and carries deoxygenated blood to the lungs where it is oxygenated and the CO2 is removed
Pulmonary vein
Connected to the left atrium and brings oxygenated blood back from the lungs
Vena cava
Connected to the right atrium and brings deoxygenated blood back from the tissues except the lungs
Why is the heart myogenic
Due to its ability to initiate its own contractions
Sinoatrial node
Located in the wall of the right atrium
Region of specialisedfibres which is the pacemaker of the heart
Role of sinoatrial node as pacemaker
Initiates a wave of electrical stimulation which causes the atria to contract at roughly the same time
Why do the ventricles not start contractin until the atria have finished?
Due to the presence of tissue at the base of the atria which is unable to conduct the wave excitation