3- somatosensory system Flashcards

1
Q

which modalities carried by spinothalamic system

A

temperature, pain, pressure or crude touch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

which modalities carried by dorsal column medial lemnisucs system

A

vibration, proprioception, fine touch, two point discrimination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what does strong receptor activation cause

A

high frequency of action potentials in primary sensory neurone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are rapidly adaptive receptors

A

fire rapidly at start then adapt and fire slowly. eg. mechanoreceptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are slowly adaptive receptors

A

fire at steady rate. eg. nociceptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is a receptive field

A

an area of skin supplied by a single primary neurone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

describe relationship between the size of receptive field and sensory acuity

A

as receptive field size increases, sensory acuity decreases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is sensory acuity

A

the ability to have two point discrimination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

why is topographical representation important

A

reduces the amount of building material eg. myelin needed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

describe the dorsal column medial lemniscus system

A
  • 1st order neurone ascend through gracile fasiculus (T7 below) or cuneate fasiculus (T7 above) to the cuneate nucleus in medulla
  • the second order neurones cross the midline and project to contralateral thalamus in the medial lemniscus
  • the third order neurones receive information from gracile nucleus (Lower half) project to medial part of primary sensory cortex. information from cruciate nucleus (upper half) project to the lateral part of primary sensory cortex.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

describe the spinothalamic pathway

A
  • first order neurones project onto second order in the dorsal horn at the segment that they enter the spinal cord (ie. before crossing over)
  • second order neurones have cell bodies in dorsal horn. they cross over in the ventral white matter of the cord and enter the spinothalamic tract. this takes them to the thalamus
  • third order neurones in thalamus receiving information from lower body project medially, and from upper body project laterally.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

compare spinothalamic and dorsal column medial lemniscus system

A

-new axons are added medially in STT, and laterally in DCML. this means that a central cord lesion affects cervical first in STT and lumbar first in DCML

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is the purpose of lissaeurs tract

A

allows first order neurones in STT to ascend before synapsing with second order neurones in spinal cord. this means that if there is spinal cord damage, there is less damage to the STT as their neurones ascend more before synapsing. DCML will be more damaged.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is brown-sequard syndrome and what is destroyed unilaterally

A

complete cord hemisection causing destruction of one lateral half of a single cord segment resulting from trauma or ischaemia. destroys dorsal and ventral horn, alll cord grey matter, all white matter pathways, dorsal and ventral rootsq

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

symptoms brown-sequard syndrome

A

ipsilateral complete segmental anaesthesia affecting a single dermatome, ipsilateral loss of dorsal column modalities below destroyed segment. contralateral loss of spinothalamic at or below destroyed segments ( may be lower due to lisseurs tract)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

describe how pain is sensed

A
  • C fibres detect pain and send first order neurone into spinal cord. synapse with second order neurone in derail horn.
  • if you rub the area of pain, it sends AB fibres that stimulate inhibitory interneurone which inhibits the second order sensory neurone. reduces pain transmission
  • in extreme pain the brain can also modulate this
17
Q

describe brain modulation of pain in cases of hypnosis or extreme pain

A
  • primary neurone synapse with secondary neurone in area of midbrain called peri-aquaductal grey
  • secondary neurone synapses with third order Nerone medulla region called nucleus raphe Magnus (NRM)
  • the neurone from NRM inhibits the second order pain neurone in spinothalamic tract.