3-Neuroscience Flashcards
Dualist framework
person who created it + definition
René Descartes
The brain acts as the link between mental processes and the body
Neuron anatomy
zones + structures in each
Receptive zone
- Dendrites
- Cell body
Transmission Zone
- Axon
- Axon terminal
- Terminal boutons
Dendrites
purpose/function
- reach out to neurons
- receive signals
Cell body (neuron)
purpose/function
- carries genetic info (nucleus)
- maintains structure
- provides energy
Axon
purpose/function
- transmits signal
- varies in length (cm to ft long)
Axon Terminal + Terminal Boutons
purpose/function
- reach out and connect to other neurons
Action potential
trigger: effect on EP –> effect on channels
- Stimulus: increase EP –> Na channels open
- Na enters cell: EP increases to +ive –> K channels open
- K leaves cell: EP still rising –> Na channels close
- K continues to leave cell: EP decreases just below resting potential –> K channels close
- Sodium potassium pump and Leak potassium channels return EP to baseline
Action Potential
important voltages name + value
- 70mV: Resting potential
- 50mV: Threshold for action potential
Refractory period
types + events under this period
Absolute RP: impossible to trigger another AP
- Na or K channels are opened, cannot be reopened
Relative RP: another AP is possible but more difficult
- larger stim needed as EP is below resting potential
- OR EP is below threshold but K channels still open
message encoding
via action potentials
messages encoded via frequency of action potentials, not intensity
Glial cells
purpose
Help neurons with:
- structural support
- nourishment
- insulation
Myelin sheaths
description + purpose + types and their location
cells which coat segments of the axon
- allow for faster conduction of AP’s through saltatory conduction
CNS: Oligodendrocytes
PNS: Schwann cells
Nodes of Ranvier
description + purpose
uncovered segments of axon between myelin sheaths
- limit where ions from APs can diffuse in and out
Synapse
description + purpose
junction between presynaptic and postsynaptic neuron
- where communication between neurons occurs
Anatomy of a synapse
major structures + important structures within them
- Presynaptic neuron
- vesicles containing NT’s
- Synapse & synaptic cleft
- Postsynaptic neuron
- receptors
Steps for neurotransmission
across a synapse
- AP triggers vesicles containing NT’s to fuse with cell wall
- NT floats in synaptic cleft
- NT binds to postsynaptic receptor
- transmission continues via excitatory or inhibitory post synaptic potential
Methods of neurotransmission
types + description + purpose
EPSP (excitatory PSP)
- Depolarization: modify ion channels to increase EP in next neuron. eg: allow Na in
- makes AP easier or triggers AP
IPSP (inhibitory PSP)
- Hyperpolarization: modify ion channels to decrease EP in next neuron. eg: allow Cl in
- makes AP more difficult to trigger
PSP: post synaptic potential
Neural Development
Neural differentiation
Neuron Maturation
3 facts about it
- neurons mature by connecting with other neurons
- only connected neurons survive
- # of synapses peaks at 1 year old
Neuraxis
6 terms
Rostral - Caudal: towards frontal lobe - towards brain stem
Ventral - Dorsal: towards the stomach/chin - towards the back/top of the head
Medial - Lateral: towards - away from the midline of the body
Neuroimaging techniques
2 basic categories
Structural
Functional