3 - Grover - Sensory Receptors Flashcards

1
Q

Two Main Receptor Categories

A

Nonencapsulated

Encapsulated

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2
Q

Nonencapsulated Receptors

A

Bare terminals of myelinated and unmyelinated axons in contact with epithelial cells of skin

Ex:

Mechanical/thermal

Itch

Pain (nociceptors)

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3
Q

Merkel Endings

A

Disk-shaped terminal of myelinated axons

Contact merkel cells (vessicle holders), resembles synapse

Mechanoreceptors

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4
Q

Hair Follicle Receptors

A

Bending of hair distorys axon membrane opening stretch gated channels

Mechanoreceptors

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5
Q

Mechanoreceptors

A

Contain stretch gated cation channels

Pressure applied to skin is transmitted through capsule to the axon ending

Capsule alters transmission of pressure to sensory endings

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6
Q

Meissner Corpuscle

A

Stacked layers of Schwann cells

Located under epidermis of hairless (glabrous) skin

Mechanoreceptors

Light Pressure, Textures, Edges

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7
Q

Pacinian Corpuscle

A

Subcutaneous

Concentric layers of epithelial cells with fluid filled spaces

Single axon ending in center of corpuscle

mechanoreceptors

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8
Q

Ruffini Endings

A

Demis, subcutaneous, and connective tissue

Capsule contains collagen strands with intertwined axon endings

Stretching of skin applies tension to collagen–squeezing axon endings

Mechanoreceptors

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9
Q

What determines adaptation rate for encapsulated receptors?

A

Phsycial properties of capsule

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10
Q

How do Pacinian Corpuscles adapt?

A

Rapid Adaptation

Respond to sustained indentation with transient ctivity at onset and offset of stimulus–layers rearrange

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11
Q

Where will action potentials be generated?

(1, 2, 3, or 4)

A

2 and 4

None generated at 3

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12
Q

How do Pacinian Corpuscle’s best respond to changes?

A

Most sensitive to fast vibrations–fast change in pressure

“Event Detectors” - grasping an object in hand

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13
Q

Tuning Curve

A

Plots intensity vs frequency

Most sensitive at frequency where threshold intensity is lowest

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14
Q

Meissner Corpuscle Tuning?

A

Tuned to respond to lower frequencies of vibration than Pacinian Corpuscle

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15
Q

How do hair follicles adapt?

A

Rapid–stop firing when bent position is held

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16
Q

What are slowly adapting receptors?

A

Merkel Receptors (skin indentation)

Ruffini Receptor (stretching)

Free Nerve Endings (some can be rapid)

17
Q

Low vs High Threshold Receptors

Free Nerve endings that function as mechanoreceptors are what type?

Examples?

A

Low = high sensitivity

High = low sensitivity

Free nerve endings that function as mechanoreceptors are high threshold

- - -

Low Threshold = Meissner, Merkel, Ruffini, Pacinian, Hair Follicle

18
Q

Where are Meissner’s corpuscles located?

A

Glabrous (hairless) skin

Hands, Feet (sensitive areas)

19
Q

Receptive Field

What does a small receptive field size indicate?

A

Spatial location where a stimulus is effective for activating a single receptor cell

  • -

Small receptive field = high spatial resolution

20
Q

Where are receptive fields the smallest and largest?

What are the relative sizes for Meissner, Merkel, Ruffini, and Pacinian?

A

Smallest on digits of hands, largest on trunk and limbs

Large = Pacinian / Ruffini

Small = Meissner / Merkel

21
Q

What type of receptors does Two-point Discrimination rely on?

A

Merkel/Meisner (small)

22
Q

How do Merkel Cell receptors best function?

A

Signal weight, form, suface features

Best: Sustained response, steady pressure exerted by edges of objects held in hand

23
Q

What is the most abundant receptor in the hand?

What are they best used for?

A

Meissner Corpuscle

Best used to detect tectures and edges as the hand is moved over surfaces

24
Q

What does the combination of Merkel and Meissner receptors provide?

A

High spatial and high temporal resolution

25
Q

Ruffini Endings functions

A

Respond to stretching of skin

Signal posture and movements of body

LIMB POSITION

26
Q

Nociceptors

Itch Receptors

A

Respond to noxious mechanical, thermal, and chemical stimuli

  • -

Respond to chemical stimuli, including histamine

27
Q

Free Nerve mechanoreceptors

A

Respond to non-noxious mechanical stimuli with low sensitivity/high threshold (crude touch sensation)

28
Q

Joint Receptors:

Free Nerve Endings

Ruffini Endings

Pacinian Corpuscles

A

Free Nerve = joint pain

Ruffini = Around joints, movements/stretching

Pacinian = Bone vibration (jackhammer)

29
Q

A-beta Fibers

A

Most cutaneous mechanoreceptors;

Large diamete

Myelinated

FAST conduction velocity

30
Q

A-delta Fibers

A

Hair follicle , some free nerve endings

Small Diameter

Light myelination

SLOW conduction

31
Q

C-fibers

A

Small diameter

UNMYELINATED axons of free nerve endings

32
Q

Fast vs Slow Pain Response

A

A-delta = FAST (sharp, pricking, localized)

C-fiber = SLOW (aching, throbbing, burning)

33
Q
A