3: COPD Epidemiology Flashcards

1
Q

Alpha-1 antitrypsen deficiency is associated with both COPD and what?

A

Liver disease

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2
Q

Is alpha-1 antritrypsin deficiency related to the chronic bronchitis or emphysema component of COPD?

A

Emphysema

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3
Q

In asthma, damage is potentially _____, but in COPD damage is _____.

A

In asthma, damage is potentially reversible, but in COPD damage is not reversible.

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4
Q

4 risk factors for COPD.

A
  1. Smoking: heavy and light smokers, active or passive
  2. Exposure to particles: via air pollution and/or work environment
  3. Increased infections throughout your life in conjunction with other factors
  4. Genetic factor: alpha-1 antitrypsin deficiency
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5
Q

What autosomal recessive disorder can lead to COPD and is usually the case with COPD diagnosis under age 40?

A

Alpha-1 Antitrypsin Deficiency

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6
Q

What factors may indicate hereditary emphysema that is difficult to diagnose in the presence of asthma?

A
  1. Family history of early-onset lung disease or childhood liver disease
  2. Shortness of breath that gets worse over years, not related to attacks of wheezing
  3. Early development of emphysema in alpha 1-ATD is associated with current or prior cigarette smoking
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7
Q

COPD is characterized by what?

A

Obstruction of airflow

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8
Q

What 2 pulmonary conditions comprise COPD?

A
  1. Chronic bronchitis
  2. Emphysema
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