3/27/21 Flashcards

1
Q

Features of physiologic jaundice

A

jaundice peaks between days 2-5
increases less than 5 mg/dl in 24 hours
bilirubin levels return to normal by 2 weeks

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2
Q

Jaundice and anemia is concerning for _____

A

hemolysis

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3
Q

Physiologic jaundice has

a) conjugated or
b) unconjugated bilirubin

A

unconjugated

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4
Q

jaundice that lasts longer that 12 days

A

is NOT physiologic

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5
Q

What is considered severe hyperbilirubinemia

A

25 mg/dl or higher

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6
Q

What is a complication of severe hyperbilirubinemia

A

bilirubin induced neurologic dysfunction

  • bilirubin encephalopathy and if not promptly treated -
  • chronic bilirubin encephalopathy (kernicterus)
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7
Q

Causes of significant unconjugated hyperbilirubinemia

A

hemolytic disease, polycythemia, hematoma
increased enterohepatic circulation (breast milk jaundice)
poor lactation and thus hypovolemia

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