2SQ1 Flashcards

1
Q

dup17p11.2

A

Sub band - 1 (Potocki Lupski)

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2
Q

basta yung picture sumama chromosomes s isang pole imbis n maghiwalay

A

Nondisjunction

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3
Q

Which of these scientists provided proof of this concept of the process previously identified (Nondisjunction)

a.) Sutton
b.) Bovari
c.) Bridges
d.) Hunt-Morgan

A

c.) Bridges

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4
Q

Odd man out, choose which one is not part of the group in terms of the biochemistry of this structure:

a.) DNA
b.) Scaffold
c.) Histone
d.) CSPs Chromosomes - All others are proteins

A

a.) DNA

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5
Q

These structure (karyotype) consist of:

a.) DNA
b.) RNA
c.) Protein
d.) All of the above

A

d.) All of the above

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6
Q

Which of the following is NOT TRUE regarding the following structure?

a.) Primary constriction where sister chromatids are linked
b.) Consists of several hundred kilobases of repetitive DNA
c.) Prevents abnormal end-to-end fusion of chromosomes
d.) Responsible for chromosome movement at cell division

A

c.) Prevents abnormal end-to-end fusion of chromosomes

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7
Q

Chromosomed can be classified based on:

a.) number of chromosomes
b.) position of centromeres
c.) based on arms ratio
d.) all of the choices

A

d.) all of the choices

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8
Q

Which of the following is a correct classification of chromosomes based on the number of centromeres?
I. Monocentric, II. Metacentric, III. Submetacentric

a.) I only
b.) I, II
c.) I, II, III
d.) I, II, III, IV

A

a.) I only

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9
Q

Morphologically, the following chromosome is: Y

a.) Metacentric
b.) Submetacentric
c.) Acrocentric
d.) Subtelometric

A

c.) Acrocentric

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10
Q

In this kind of chromosomes, the centromere is located very close to the end of the chromosome that the p arms would not, or barely, be visible. This chromosomes are not present in healthy humans.

a.) 1st is correct, 2nd is incorrect
b.) 1st is incorrect, 2nd is correct
c.) Both statements are correct
d.) Both statements are incorrect

A

c.) Both statements are correct

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11
Q

True of the above chromosomes (dicentric):

a.) reliably passed from parental to daughter cells
b.) is left at the metaphase plate at anaphase because they lack kinetochores
c.) is the broken fragment left after breaking off from a chromosomal fragile site
d.) fused chromosomes in cases precipitated by Robertsonian translocation

A

d.) fused chromosomes in cases precipitated by Robertsonian translocation

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12
Q

Select all that is true of the structure (white, telomeres):

a.) present only in nonlinear DNAs of eukaryotes
b.) passed through the matrilineal line
c.) anchors chromosomes to nuclear walls in meiosis
d.) shortens over time with age

A

C & D

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13
Q

_____ a structure that occurs when a chromosome breaks into two places and its broken ends fuse together.

A

Ring

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14
Q

Identify this kind of chromosomal aberration that is a product of translocation (BCR-ABL gene)

A

Gene fusion

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15
Q

P arm length is 1; Q arm length is 1

a.) biggest chromosome in karyotype
b.) last and penultimate autosomes, and male determining chromosome
c.) some chromosome of the Shamrock species of plants
d.) female sex chromosome (2 of them)

A

a.) biggest chromosome in karyotype (Metacentric)

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16
Q

P arm length is 0.5, Q arm length is 1.5

a.) biggest chromosome in karyotype
b.) last and penultimate autosomes, and male determining chromosome
c.) some chromosome of the Shamrock species of plants
d.) female sex chromosome (2 of them)

A

d.) female sex chromosome (2 of them) (Submetacentric)

17
Q

P arm length is 0.2, Q arm length is 1.2

a.) biggest chromosome in karyotype
b.) last and penultimate autosomes, and male determining chromosome
c.) some chromosome of the Shamrock species of plants
d.) female sex chromosome (2 of them)

A

b.) last and penultimate autosomes, and male determining chromosome (Acro)

pero dapat daw Subtelo

18
Q

The s_____d structure of chromatin is a model for the structure of the 30nm fibre. It is a secondary chromatin structure which helps to package DNA into the nucleus.

A

Solenoid

19
Q

Identify this chromosomal alteration: i(X)(q10)

A

Isochromosome

20
Q

BONUS: In cytogenetics, the naming of chromosomal aberrations such follows notations like the 22q11.2 (Digeorge Syndrome). The one one point notation part is made possible by s____g of the transcriptionally active regions of the chromosome known as bands, sub bands or sub sub bands.

A

staining

21
Q

BONUS: Name this part of this molecule used to spool 147 bases, - DNA: L_____ subunit

A

Linker