2F: Protein Secretory Pathway

Question 1

What is the protein secretory pathway

Answer 1

primarily involves the use of ribosomes, Rough ER, Golgi apparatus and transport vesicles to fold, modify, and package proteins, eventually exporting them from the cell via the process of exocytosis.

Question 2

Ribosome

Answer 2

an organelle made of rRNA and protein that is the site of protein synthesis.

• Can either float free in the cytoplasm or be attached to the RER

Question 3

Bulk Transport

Answer 3

a type of active transport that uses vesicles to move large molecules or substances in or out of the cell

Question 4

Exocytosis

Answer 4

a type of bulk transport that moves large substances out of the cell

- Can export waste products or proteins
- Done through the use of motor proteins

Question 5

Process of Exocytosis

Answer 5

1. Vesicles containing secretory products are transported to the plasma membrane
2. the membrane of the vesicle fuses with the plasma membrane
3. The secretory products are released from the cell into the extracellular environment

Question 6

Rough ER role in PSP

Answer 6

involved in folding and transporting proteins that are being synthesized on ribosomes attached to the RER

Question 7

Transport Vesicle role in PSP

Answer 7

buds off of the RER containing the protein and transports it to the golgi body

Question 8

Process of the protein secretory pathway

Answer 8

Ribosome > RER > Transport Vesicle > Golgi Apparatus > Secretory Vehicle via exocytosis

Question 9

Golgi Apparatus

Answer 9

modifies proteins by either adding or removing chemical groups before packaging into a secretory vesicle

Question 10

Secretory Vesicle

Answer 10

• Budd off the Golgi body containing proteins for export - travel through the cytoplasm, fusing with the membrane
• Releases proteins into the extracellular environment(exocytosis)