28. Immunodeficiency Diseases I

Question 1

Would AIDS be classified as a primary or secondary immune deficiency? Why?

Answer 1

AIDS = aquired immunodeficiency syndrome is a secondary immune deficiency because it results from the infection of HIV

Question 2

What type of deficiency would a patient with a decreased number of CD19-positive cells have? List one example of this type of deficiency.

Answer 2

Humoral Immunity (antibody) deficiency. An Example is X-linked Agammaglobulinemia.

Question 3

What type of deficiency would a patient showing decreased proliferation in response to the mitogen, PHA, have?

Answer 3

PHA typically causes proliferation in T cells. Therefore, this patient has cell-mediated immunodeficiency.

Question 4

What type of deficiency would a patient showing a negative anergy panel have?

Answer 4

Cell-mediated immunodeficiency

Question 5

What is the name of an X-linked immune deficiency in which patients have decreased levels of serum immunoglobulins and a decreased number of peripheral blood B lymphocytes?

Answer 5

X-linked Agammaglobulinemia

Question 6

Which type of selective immunoglobulin deficiency is most common?

Answer 6

Selective IgA deficiency

Question 7

What types of immune deficiencies are gamma globulins used to treat? List an example of such a deficiency.

Answer 7

Humoral Immunodeficiency. An example is Common Variable immunodeficiency.