2. Cells and Tissues of the Immune System

Question 1

Which cells are responsible for antibody production?

Answer 1

Plasma Cells (B cells)

Question 2

Which cells can help or suppress immune responses?

Answer 2

T lymphocytes

Question 3

Which cells are involved in antigen presentation to T cells?

Answer 3

Macrophages and Dendritic cells

Question 4

Which cells are able to phagocytize foreign material?

Answer 4

Neutrophils and Eosinophils

Question 5

Which cells have a role in allergic reactions?

Answer 5

Eosinophils (regulate) and Basophils

Question 6

From what organs do the T and B lymphocytes originate?

Answer 6

T lymphocytes = differentiate in the Thymus

B lymphocytes = differentiate in the Bone Marrow (or Bursa of Fabricius)

Question 7

What is the role of the lymph nodes in the immune response?

Answer 7

• collects AG from intracellular tissue fluids turning primary follicles into secondary follicle with germinal center.
• contains about 75% T cells and 15% B cells

Question 8

What is the role of the spleen in the immune response?

Answer 8

• filters bloodborne antigens

- contains about 40% T cells and 50% B cells

Question 9

Where are the T lymphocytes located in the thymus?

• in the lymph nodes?
• in the spleen?

Answer 9

Thymus:
Cortex = receives immature T cells
Medulla = receives cell from cortex become mature T cells

Lymph Node = Paracortex

Spleen = PALS (perilaterial lymphatic sheath)

Question 10

Where are the B lymphocytes located in the lymph nodes?

- in the spleen?

Answer 10

Lymph Node = Cortex

Spleen = Follicle

Question 11

T lymphocytes constitute approximately what percent of mononuclear cells in the peripheral blood?

Answer 11

75%

Question 12

B lymphocytes constitute approximately what percent of mononuclear cells in the peripheral blood?

Answer 12

15%

Question 13

What cells are the CD2 and CD3 surface markers found on?

Answer 13

T cells

Question 14

What cells are the CD19 and CD20 surface markers found on?

Answer 14

B cells