2.7

Question 0

When blood is transfused, it is important that people are given blood of the

Answer 0

Correct blood group

Question 1

People with sickle-cell anaemia may need to be given a

Answer 1

Blood transfusion

Question 2

Blood groups are determined by the

Answer 2

Antigens present on the red blood cells -

These antigens are inherited

Question 3

There are several antigens present in this blood group, but the main one is known as

Answer 3

Antigen D

Question 4

People who have antigen D on their red blood cells are

Answer 4

Rhesus positive

Question 5

Antigen D is codes do by the dominant allele,

Answer 5

D

Question 6

People who do not have antigen D on their red blood cells are

Answer 6

Rhesus negative

Question 7

People who are rhesus positive may have the genotype

Answer 7

DD or Dd

Question 8

People who are rhesus negative have the genotype

Answer 8

dd

Question 9

It is possible for a rhesus negative mother to be pregnant with a rhesus positive baby. The mother’s blood and the baby’s blood do not mix in the placenta. However it is possible for the baby’s blood to come into

Answer 9

Contact with the mother’s blood around the time of childbirth

Question 10

When mother’s blood and baby’s blood comes into contact, the mother’s immune system will make

Answer 10

Antibodies against the rhesus antigen

Question 11

If the mother becomes pregnant with a second rhesus positive baby, problems may be more severe. Antibodies pass from the mother’s blood to the baby’s across the

Answer 11

Placenta

Question 12

The mother’s anti-rhesus antibodies pass across the placenta and attack the baby’s red blood cells. This destroys them and causes severe anaemia. The condition is called

Answer 12

Haemolytic disease of the newborn

Question 13

Haemolytic disease of the newborn varies in severity in mild forms the baby is born with

Answer 13

anaemia and jaundice

Question 14

Haemolytic disease of the newborn in severe cases the baby may develop

Answer 14

Respiratory arrest or heart failure

Or even still born

Question 15

Haemolytic disease of the newborn can be prevented by giving pregnant women who are rhesus negative an

Answer 15

Injection of anti-rhesus globulin and repeating the injection after the birth of a rhesus positive baby.

Question 16

(Haemolytic disease of the newborn) if the injection is done the mother should be have to have further

Answer 16

Rhesus positive babies without any risk

Question 17

The best known blood group system is the

Answer 17

ABO system

Question 18

There are 4 blood groups in this system:

Answer 18

A
B
AB
O

Question 19

People with group A have:

Answer 19

A antigens on their RBC

Question 20

Group B=

Answer 20

B antigens on their RBC

Question 21

Group AB have:

Answer 21

Both kinds of antigen

Question 22

Group O have:

Answer 22

Neither of these antigens on their RBC

Question 23

People with different blood groups also have different

Answer 23

Antibodies on their plasma

Question 24

When a person is given a blood transfusion it is important that the antigens of the donor should be compatible with the antibodies of the

Answer 24

Recipient

Question 25

If a person is given blood of the wrong blood group, their antibodies clump the donor RBC known as

Answer 25

Agglutination

Question 26

Agglutination can block

Answer 26

Blood vessels and can be fatal

Question 27

ABO blood groups are inherited they are determined by a single gene with 3 different alleles. This is an example of inheritance involving

Answer 27

Multiple alleles

Question 28

Two alleles IA and IB are co dominant while IO is

Answer 28

Recessive