25 Nov Flashcards

1
Q

Drug that cause hypothyroidism

A

Amiodarone
Lithium

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2
Q

What, is the type of lymphoma that is associated with hashmito thyroiditis

A

Non Hodgkin b cell lymphoma

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3
Q

Incidence of thyroid cancer

A

13.5 /100k

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4
Q

Cause of papillary thyroid carcinoma

A

①radiation ② BRAF mutation ③ ret/ptc
rearrangement

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5
Q

Causes of follicular carcinoma

A

Pax8/ppar-gama rearrangement

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6
Q

Causes of medullary thyroid carcinoma

A

RET mutation (MEN2 syndrome )

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7
Q

Most common thyroid cancer

A

Papillary thyroid cancer

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8
Q

Where does follicular thyroid cancer spread

A

Lung and bone

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9
Q

How does papillary CA spread

A

By lymph node

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10
Q

How does follicular.ca spread

A

Hematogenous

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11
Q

What is the paraneoplastic syndrome that associated with medullary CA

A

Diarrhea ,flushing

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12
Q

Red flag of thyroid nodule

A

Male
Extreme ages
Family history
Radiation history
Dysphagia/hoarseness/dyspnea
Firm,hard,not moving
Cervical lymphadenopathy

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13
Q

Sign on ultrasound that suggest thyroid malignancy

A

Solid
Hypoechoic nodule
Irregular margin
Micro calcification
Nodule taller than other
Extra thyroid growth
Increase vascularity
Halo sign

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14
Q

Pathology of papillary thyroid CA

A

1-psamomma bodies
2-orphan Ann eye
3-nuclear groove

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15
Q

Pathology of follicular CA

A

Follicular patter
Vascular/capsular invasion

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16
Q

Pathology of medullary thyroid ca

A

Amyloid

17
Q

Well differentiate thyroid cancer

A

Papillary and follicular

18
Q

Mutation that associated with bad prognosis papillary thyroid cancer

A

BRAF mutation

19
Q

What is thyroid cancer that have poor radioactive iodine intake

A

Medullary and anaplastic cancer

20
Q

What is the best imaging modalities to assess the invasion of thyroid cancer

A

CT scan

21
Q

Original of thyroid gland

A

Epithelial cell

22
Q

Original of parathyroid gland

A

3rd and 4th pharyngeal pouch

23
Q

ECG finding of hypercalcemia

A

Bradycardia
QT shortening
Arrthymia

24
Q

What is the most common type of choledocal cyst that may transform to cancer

A

Type 4

25
Q

What is the gold standard imaging to Dx choledocal cyst

A

MRCP

26
Q

What is the genetic mutation that is associated with chronic pancreatitis

A

PRSS1 and SPINK1

27
Q

First line pain drug for chronic pancreatitis

A

NSAID

28
Q

What is the MRCP finding of PSC

A

Beading of bile duct

29
Q

What is the most common cause of cirrhosis

A

Hepatitis B

30
Q

What is the mode of inheritance of FHH

A

Autosomal dominant