25 Nov Flashcards
(30 cards)
Drug that cause hypothyroidism
Amiodarone
Lithium
What, is the type of lymphoma that is associated with hashmito thyroiditis
Non Hodgkin b cell lymphoma
Incidence of thyroid cancer
13.5 /100k
Cause of papillary thyroid carcinoma
①radiation ② BRAF mutation ③ ret/ptc
rearrangement
Causes of follicular carcinoma
Pax8/ppar-gama rearrangement
Causes of medullary thyroid carcinoma
RET mutation (MEN2 syndrome )
Most common thyroid cancer
Papillary thyroid cancer
Where does follicular thyroid cancer spread
Lung and bone
How does papillary CA spread
By lymph node
How does follicular.ca spread
Hematogenous
What is the paraneoplastic syndrome that associated with medullary CA
Diarrhea ,flushing
Red flag of thyroid nodule
Male
Extreme ages
Family history
Radiation history
Dysphagia/hoarseness/dyspnea
Firm,hard,not moving
Cervical lymphadenopathy
Sign on ultrasound that suggest thyroid malignancy
Solid
Hypoechoic nodule
Irregular margin
Micro calcification
Nodule taller than other
Extra thyroid growth
Increase vascularity
Halo sign
Pathology of papillary thyroid CA
1-psamomma bodies
2-orphan Ann eye
3-nuclear groove
Pathology of follicular CA
Follicular patter
Vascular/capsular invasion
Pathology of medullary thyroid ca
Amyloid
Well differentiate thyroid cancer
Papillary and follicular
Mutation that associated with bad prognosis papillary thyroid cancer
BRAF mutation
What is thyroid cancer that have poor radioactive iodine intake
Medullary and anaplastic cancer
What is the best imaging modalities to assess the invasion of thyroid cancer
CT scan
Original of thyroid gland
Epithelial cell
Original of parathyroid gland
3rd and 4th pharyngeal pouch
ECG finding of hypercalcemia
Bradycardia
QT shortening
Arrthymia
What is the most common type of choledocal cyst that may transform to cancer
Type 4
