2.4 Myeloid Flashcards

1
Q

AKA Colony forming units

A

Progenitor cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

AKA hemopoietic cytokines

A

Colony-stimulating factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Source of TPO

A

Kidney and liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Source of EPO

A

Kidney and hepatocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

ECM composition of bone marrow

A

Collagen tupe IProteoglycansFIbronectinLaminin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Marrows of newborns

A

Red bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Marrows of adults

A

Yellow bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Stimulates production of RBCs in the bone marrow

A

Hemopoietic growth factor, erythropoietin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Stage of erythrocyte maturation where hemoglobin synthesis starts but is not significant enough to change the color of the cytoplasm

A

Basophilic erythroblast stage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Stage in erythrocyte maturation where hemoglobin synthesis is more significant and characterized by lilac color due to presence of both pasiphilia and acidophilia

A

Polychromatic erythroblast stage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Earliest and first recognizable stage of the RBC maturation

A

Proerythroblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Stage with checkerboard patternStart of synthesis of Hgb

A

Basophilic erythroblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Stage with lilac color of rbc maturation, more condense nucleusAfter this stage, mitotic activity ceases

A

Polychromatophilic erythroblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

RBC stage similar to a mature erythrocyteFried egg appearanceNucleus is found at one sideAcidophillic cytoplasm

A

Orthochromatophilic erythroblast (normoblast)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Most immature recognizable cell in the myeloid series

A

Myeloblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Stage of granulocyte maturation with basophilic cytpolasm + non-specific azurophilic granules

A

Promyelocyte

17
Q

Stage of granulocyte maturation with 1st visible sign of differentiationSpecific granules beginOvoid nucleus

A

Myelocyte

18
Q

Stage of granulocyte maturation with deeply indented nucleus, and specific granules

A

Metamyelocyte

19
Q

Total time taken for a myeloblast to emerge as a mature neutrophil is about ___ days

A

11 days

20
Q

Platelets are fragments of ___

A

Megakaryocyte

21
Q

Invaginations of plasma membrane throughout the cytoplasm of the megakaryocyteServes as a membrane reservoir for continuous and rapid proplatelet elongation

A

Demarcation membranes

22
Q

Mitotic compartment of granulocytes

A

Granulopoietic compartment

23
Q

Granulopoietic compartment which acts as a buffer system; releases neutrophils on demandStores neutrophils up to 4 days

A

Storage compartment

24
Q

Compartment of neutrophils in capillaries and endothelium

A

Marginating comparment