2.3- the biology of controlling fertility Flashcards
what type of fertility do men have and why is this?
continuous fertility
continually produce sperm in their testes
what is cyclical fertility and what does it lead to?
when women are only fertile for a few days during each menstrual cycle
leads to a fertile period
2 things that identify the fertile period
womans body temperature increases around 0.5° after ovulation
cervical mucus becomes thin and watery
what does thin and watery cervical mucus allow for?
gives sperm easy access to the female reproductive system
how long does the fertile period last?
1-2 days
what happens after the third recording of higher temperature?
unfertilised egg is disintegrated
4 treatments for infertility
stimulating ovulation
artificial insemination
intra-cytoplasmic sperm injection (ICSI)
in-vitro fertilisation (IVF)
how does stimulating ovulation work?
ovulation stimulated by drugs that prevent the negative feedback effect of oestrogen on FSH secretion
what do other ovulatory drugs do and what do they cause?
mimic the action of FSH and LH
cause super ovulation that can result in multiple births or be used to collect ova for in-vitro ovulation programmes
what does artificial insemination involve?
several samples of semen are collected over a period of time
when is artificial insemination useful?
when male has a low sperm count
how does intra-cytoplasmic sperm injection work?
head of the sperm is drawn into a needle and injected directly into the egg to achieve fertilisation
when is intra-cytoplasmic sperm injection useful?
when mature sperm are defective or very low in number
what does in-vitro fertilisation intend to do?
solve infertility caused by a blockage in the oviduct
6 steps of IVF
woman is given hormonal treatment to stimulate multiple ovulation
surgical procedure employed to remove several of these eggs from her ovary
eggs mixed with sperm in culture dish to allow fertilisation to occur (ICSI can be used)
fertilised eggs incubated in culture dish for 2-3 days to allow cell division to occur and they have formed at least 8 cells
a few embryos are chosen and then inserted via the vagina into the mothers uterus
remaining embryos frozen and stored if a second attempt at implantation is needed
what can IVF be used in conjunction with and what 2 things can they identify?
pre-implantation genetic diagnosis
identify single gene disorders and chromosomal abnormalities
when is pre-implantation genetic diagnosis used in IVF and what happens?
before stage 5 takes place
one or two cells may be removed and tested for genetic abnormalities