2.3 DNA and Inheritance Flashcards
What is DNA made up of
Two long chains of alternating sugar and phosphate molecules twisted to form a double helix
Complementary base pairing (which goes with which)
Adenine goes with Thymine
Cytosine goes with Guanine
How does the order of bases determine proteins made
The order of bases forms a code which determines the order in which different amino acids are linked to form proteins
Triplet code
3 bases = 1 triplet - codes for 1 amino acid
What does genetic profiling do
Shows similarity between 2 DNA samples
Genetic profiling steps
- A sample of cells is collected, The cells are broken up and the DNA extracted
- The DNA is cut up by enzymes into fragments of different sizes
- The fragments are separated into bands by order of length using electrophoresis
A pattern develops, this is the genetic profile
Uses of genetic profiling
Multiple patterns - genetic profiles - are compared
- Identify someone who has left DNA at a crime scene
- Determine a child’s paternity
- Comparisons between species for classification
- identify the presence of genes that are associated with a certain disease so precautions can be taken
Gene definition
A length of DNA that codes for one protein
Allele defintion
A variety of a gene - different version of the same gene e.g. gene for eye colour: one allele for blue, one allele for brown
Chromosome
A length of DNA containing many genes, found in the nucleus
Genotype
The genetic makeup of an individual in terms of alleles
Phenotype
The way the genotype is expressed
Dominant allele
That allele that always shows itself in the phenotype whenever it is present
Recessive allele
The allele that only shows itself in the phenotype when dominant allele is not present (hidden when dominant is present)
F1/F2
First generation/Second generation in a genetic cross