21.0.24 Flashcards

1
Q

Features of cold AIHA:

A

Lymphoma is a risk factor, and mycoplasma and EBV
Raynauds phenomenon
Symptoms worse in cold
Macrocytic anaemia, macrocytosis due to reticulocytosis to compensate for haemolysis

IgM antibody

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2
Q

Leukaemia cause of warm AIHA?

A

CLL

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3
Q

Mechanisms of anaemia in CKD:

A

Reduced EPO production

Reduced iron absorption

Reduced rbc lifespan e.g. haemodialysis

Reduced erythropoiesis due to uraemic toxicity on bone marrow

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4
Q

What type of cells are seen on blood film in myelofibrosis?

A

Teardrop poikilocytes

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5
Q

What type of cells are associated with HS and immune-mediated haemolytic anaemias?

A

Spherocytes

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6
Q

What type of cells are associated with haemolytic anaemia?

A

Shistocytes

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7
Q

What conditions present with a positive direct Coomb’s test?

A

Acquired, immune causes:
AIHA
Mycoplasma infection
Transfusion reaction
HDN
Methyldopa
Penicillin

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8
Q

Mechanism of anaemia in HL:

A

AIHA, coombs positive

Hypersplenism

Bone marrow replacement by HL

Normocytic usually

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9
Q

Causes of warm vs cold AIHA:

A

Warm:
Idiopathic
SLE/AI disease
Lymhpoma
CLL
Methyldopa

Cold:
lymphoma
mycoplasma
EBV

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10
Q

Mnemonic for asthma treatment:

A

O SHIT ME

Oxygen

Salbutamol o2 nebs
Hydrocortisone IV/ Pred oral
Ipratropium bromide nebs
Theophylline - aminophylline infusion

Mag sulphate
Escalation e.g. intubation, ITU

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11
Q

3 investigations in MS:

A

MRI Brain and Spine with gadolinium contrast (disseminated in time and space and demyelination)

LP with oligoclonal bands

Visual evoked potentials (slowed conduction of nerve signals in the optic nerve)

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12
Q

Delirium definition:

A

Acute fluctuating altered level of consciousness with inattention and disorganised thinking.

Causes include PINCH ME:
Pain
Infection
Nutrition
Constipation
Hydration

Medication
Environment

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13
Q

Management of delirium:

A

Treat underlying cause

Orientate patient

Review medications

Ensure adequate fluid balance

Haloperidol / risperidone / benzos as last resort.

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14
Q

Most common organism in lactational mastitis / abscess?

A

Staph aureus

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15
Q

Investigation and management of a breast abscess:

A

US to visualise abscess and guide drainage procedure

Needle aspiration, for culture and drainage

Incision and drainage or needle aspiration under US

PO or IV abx depending on severity

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16
Q

When to treat carotid stenosis?

A

> 50% or >70%

Carotid endarterectomy

17
Q

Most haemorrhoids can be managed conservatively. Outline 3 aspects of conservative management:

A

Lifestyle advice including increasing daily fibre and fluid intake, and weight loss.

Laxatives

Topical analgesia e.g. lignocaine gel (avoid oral opioids)

18
Q

Surgical management of haemorrhoids by degree of severity:

A

1+2 = rubber band ligation

2+3 = haemorrhoidal artery ligation

3+4 = haemorroidectomy

19
Q

Treatment of lactational mastitis:

A
  1. continue breastfeeding
  2. analgesia and warm compresses
  3. If symptoms don’t improve after 12-24 hours of effectve milkd removal treat with oral fluclox.

Other indications for abx are systemically unwell, nipple fissure present and culture indicates infection.

Continue feeding during abx.

20
Q

Most common cause of serous or bloody nipple discharge:

A

Intraductal papilloma

Benign tumour of the ductal epithelium, creates a central mass.

Manage with lactiferous duct excision (microdochectomy)

21
Q

What is involved in a Hartmann’s procedure?

A

Emergency laparotomy e.g. bowel obstruction or perf.

Complete resection of the recto-sigmoid colon.
End colostomy and closure of rectal stump.

22
Q

Definition of syncope

A

a TLOC due to transient global cerebral hypoperfusion that is characterised by rapid onset, short duration and spontaneous complete recovery

Can be split into reflex, orthostatic intolerance and cardiac

23
Q

5 frailty syndromes:

A

Instability
Intellectual impairment
Incontinence
Immobility
Iatrogenic

24
Q

4 assessments of frailty:

A

Rockwoods Frailty Index
Rockwood Clinical Frailty scale
Timed up and go test
Walking speed