2.10 Review case of the week Flashcards
causes of activated lymphocytes
EBV
HIV
any other viral URTI, RSV, influenza, parainfluenza
infected epithelial and b-cell lymphocytes
generalised T-cell reaction
EBV serology +
infectious mono
toxic granulation and vacuolation of neutrophisl indicates
infection and or tissue damage
steroids cause which white blood cell to be increased on the FBC?
neutrophils due to demargination
young female patient
disease above diaphragm
no b-symptoms, no itch, no alcohol induced pain
hodgekin’s disease
b-cell symptoms, itch and alcohol induced pain are more common in this
non-hodgkin’s lymphoma
how do you differentiate NHL and HL?
node biopsy
Reed sternberg cells
Hodgkin’s lymphoma
immature lymphocytes malignant clone
high grade NHL
mature lymphocytes are malignat clone
low grade NHL
marrow infiltration causes of leucoerythroblastic blood picture
lymphoma
non haem cancers
fibrosis
marrow stress causes of leucoerythroblastic blood picture
severe sepsis
severe bleeding
shock
hypocellular bone marrow in pancytopenia
drug induced apasia
cytotoxics
certain viruses
aplastic anaemia
hypercellular bone marrow in pancytopenia
infiltration
peripheral destruction
hypersplenism
what infections are particularly important in neutropaenia?
gram -
anaerobes
but broad spectrum coverage important
