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Transport > 210:Asthma Drugs > Flashcards

210:Asthma Drugs Flashcards

1
Q

beta agonist mechanism of action

A

Salbutamol, Terbutaline: beta 2 adrenoreceptors to relax bronchial smooth muscle

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2
Q

beta agonist side effects

A

tremor, tachycardia, hypokalaemia

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3
Q

corticosteriod: mechanism of action

A

beclomatasone, flutiasone, budesonide: reduce inflammation, hyper responsiveness and goblet cell hyperplasia (and therefore vascular permeability)

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4
Q

long acting beta agonist: mechanism of action

A

Salmeterol, Formoterol have a lipophillic side chain anchoring molecule and increasing contact time.

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5
Q

what is simbicort?

A

combined formoterol and budesonide

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6
Q

leukotriene receptor antagonist: mechanism of action

A

Montelukast : stops leukotreines binding to receptors - reduces bronchoconstriction, reduces inflammation, mucus secretion, vascular permeability and eosinophil recruitment

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7
Q

Xanthines: mechanism of action

A

theophylline, aminophylline: inhibit phosphodiesterase.

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Transport (4 decks)

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