126: Angina Drugs

Question 1

nitrates mechanism of action

Answer 1

activate and increase cGMP to cause smooth muscle relaxation. reduces venous return.

Question 2

beta blockers mechanism of action

Answer 2

reduces sympathetic drive on HR and contractility.

Question 3

Ca Channel blockers mechanism of action

Answer 3

smooth muscle relaxation via reduction of influx of Ca ions

Question 4

potassium channel activator mechanism of action

Answer 4

causes efflux of potassium and reduces calcium entry

Question 5

Ivabradine mechanism of action

Answer 5

blocks current in SA node

Question 6

ranolazine mechanism of action

Answer 6

inhibits sodium channels - reduces calcium overload - smooth muslce relaxation.

Question 7

name a nitrate

Answer 7

Glyceryl Trinitrate (GTN) or isosorbide mononitrate ( long acting)

Question 8

name a potassium channel activator

Answer 8

nicorandil

Question 9

name some beta blockers

Answer 9

bisoprolol, atenolol, metoprolol, cervedilol

Question 10

name some calcium channel blockers

Answer 10

amlodipine, nifedipine, felodipine ( Verapamil and Diltiazem are used instead of beta blockers)