2.1 Neuron Properties Flashcards
Endocrine vs. Nervous System
NERVOUS: -fast -short duration -neurons directly contact target cells to deliver neurotransmitter ‘message’ ENDOCRINE: -slow -long duration -blood delivers the hormone ‘message’
Dendrites
receive synaptic INPUTS from neuronal axons
Cell Body
Has the same organelles as any other cell
Trigger Zone
(in between the cell body and axon) Action Potentials are started here, the axon runs with them
Axon
fire rapid impulses (Action Potentials) to synaptic terminals
Presynaptic and Postsynaptic Terminals
Presynaptic release OUTPUT signal to Postsynaptic (next neuron or target tissue); release neurotransmitters at synapses
Multipolar:
Brain
Spine
Motor
Bipolar:
Retina
Ear
Nose
Unipolar:
Sensory Receptor Neurons
Why do membrane potentials exist?
becasue of electrochemical gradients: concentration gradients of charged (+/-) ions seperated by a cell membrane
When do Cellular Membrane Potentials exist?
1) Ions can be pumped (actively transported) through ion carriers embedded in the cell’s plasma membrane
2) Ions are maintained at a different concentrations on either side of the cell membrane: concentration gradient
3) The ion (the potential) can change (flux) by flowing through ion channels.
Ion Pumps
- Use primary and secondary active transport mechanisms to create ion concentration gradients
- Major ions that are pumped in neurons: Na+, K+, Cl-, Ca2+
- Requires constant source of energy or gradients ‘erode’ very quickly
Types of Ion Channels
- Passive/Leakage (nongated) Channels
- Ligand Gated Channels
- Voltage Gated Channels
- Mechanically Gated Channels
Passive/Leakage (nongated) Channels
open randomly, important in maintaing the baseline neuronal membrane potential; ion flow is sensative to concentration gradient
Ligand Gated Ion Channels
open in response to binding of a ligand (neurotransmitter, hormones, ions)