206: Cryosurgery Flashcards
What is the primary purpose of cryosurgery?
Cryosurgery is used to destroy cells of abnormal or diseased tissue using extreme cold.
What are the effects of rapid freezing in cryosurgery?
Rapid freezing causes intracellular ice crystal formation, disrupting electrolytes and pH changes, leading to cell death more readily achieved.
Which cryogen is considered the cryogen of choice in cryosurgery and why?
Liquid nitrogen is the cryogen of choice because it has the lowest temperature of all common cryogens and causes rapid freeze of treated tissue.
What are the absolute contraindications for cryosurgery?
Absolute contraindications include lesions that require histopathology for diagnosis, recurrent nonmelanoma skin cancers, and tumors with indistinct borders or darkly pigmented features.
What are some risks and complications associated with cryosurgery?
Risks and complications include pain, bleeding, pigmentation changes, nerve damage, scarring, alopecia, and insufflation of soft tissue.
What is the open spray method in cryosurgery?
The open spray method involves using a handheld cryosurgical unit with a fingertip trigger to spray from a distance of 1-2 cm, suitable for superficial lesions with specific clinical freeze margins.
What is the recommended treatment duration for seborrheic keratosis using cryosurgery?
The recommended treatment duration for seborrheic keratosis is 10-15 seconds with a 1-2 mm halo.
What is the goal of treating actinic keratosis with cryosurgery?
The goal of treating actinic keratosis is to destroy the lesion in a single treatment using an open spray, single freeze-thaw cycle of 8-10 seconds with 1-2 mm margins.
A patient presents with a small, well-circumscribed lesion in a confined location. Which cryosurgery technique would you use, and why?
The closed technique should be used because it involves pressing a copper cryoprobe against the lesion, making it ideal for small, well-circumscribed lesions in confined locations.
You are treating a patient with actinic keratosis using cryosurgery. What is the recommended freeze-thaw cycle and margin?
For actinic keratosis, an open spray method with a single freeze-thaw cycle of 8-10 seconds and a 1-2 mm margin is recommended.
A patient with cold urticaria needs cryosurgery. What should you consider before proceeding?
Cold urticaria is a relative contraindication for cryosurgery, so the procedure should be avoided or performed with extreme caution.
What is the primary reason melanocytes are highly sensitive to cryosurgery?
Melanocytes are highly sensitive to cryosurgery because they are more prone to damage from freezing, which can lead to depigmentation.
A patient undergoing cryosurgery experiences paresthesia. What is the likely cause?
Paresthesia is likely caused by nerve damage, which is a potential complication of cryosurgery.
Why is liquid nitrogen the cryogen of choice in cryosurgery?
Liquid nitrogen is the cryogen of choice because it has the lowest temperature among common cryogens, allowing for rapid freezing of treated tissue.
What is the effect of prolonged freezing (>30 seconds) during cryosurgery?
Prolonged freezing for more than 30 seconds can result in permanent pigment loss.
A patient with a dermatofibroma is undergoing cryosurgery. What is the recommended freeze time?
The recommended freeze time for a dermatofibroma is 60 seconds.
What is the primary difference between rapid and slow freezing in cryosurgery?
Rapid freezing causes intracellular ice crystal formation with disruption of electrolytes and pH changes, leading to more effective cell death, while slow freezing causes extracellular ice formation with less cell damage.
What is the role of thawing in cryosurgery, and how does it affect cell damage?
Thawing leads to recrystallization, where ice crystals fuse to form larger crystals that disrupt cell membranes. Longer thawing times result in greater cell damage.
A patient with Kaposi sarcoma is undergoing cryosurgery. What is the recommended treatment protocol?
For Kaposi sarcoma, two freeze-thaw cycles every 3 weeks are recommended, with an average of 3 treatments.
What is the most frequent cryosurgery technique, and how is it performed?
The open spray method is the most frequent technique. It involves using a handheld cryosurgical unit with a fingertip trigger to spray from a distance of 1-2 cm.
What are the absolute contraindications for cryosurgery?
Absolute contraindications include lesions that require histopathology for diagnosis and recurrent nonmelanoma skin cancers.
A patient with seborrheic keratosis is undergoing cryosurgery. What is the recommended freeze time and halo size?
For seborrheic keratosis, a freeze time of 10-15 seconds with a 1-2 mm halo is recommended.
What are the risks of using cryosurgery on lesions with indistinct borders?
Lesions with indistinct borders are a relative contraindication because it may be difficult to ensure complete treatment, increasing the risk of recurrence.
What is the primary use of electrosurgery?
Electrosurgery uses the transmission of electricity to cut tissue, destroy tissue, and cauterize vessels.