2014 Key Associations Flashcards
Actinic (solar) keratosis
Precursor to squamous cell carcinoma
Actinic (solar) keratosis
Precursor to squamous cell carcinoma
Acute gastric ulcer associated with CNS injury
Cushing ulcer (increased intracranial pressure stimulates vagal gastric secretion)
Acute gastric ulcer associated with severe burns
Curling ulcer (greatly reduced plasma volume results in sloughing of gastric mucosa)
Alternating areas of transmural inflammation and normal colon
Skip lesions (Crohn disease)
Aneurysm, dissecting
Hypertension
Aortic aneurysm, abdominal and descending aorta
Atherosclerosis
Aortic aneurysm, arch
Tertiary syphilis (syphilitic aortitis), vasa vasorum destruction
Aortic aneurysm, ascending
Marfan syndroem (idiopathic cystic medial degeneration)
Atrophy of the mammillary bodies
Wernicke encephalopathy (thiamine deficiency causing ataxia, opthalmoplegia, and confusion)
Autosplenectomy (fibrosis and shrinkage)
Sickle cell anemia (hemoglobin S)
Bacteria associated with gastritis, peptic ulcer disease, and stomach cancer
H pylori
Bacterial meningitis (adults and elderly)
Strep pneumo
Bacterial meningitis (newborns)
Group B strep/E coli
Bacterial meningitis (kids)
S pneumo, N meningitidis
Benign melanocytic nevus
Spitz nevus (most common in 1st two decades)
Bleeding disorder with GP1b deficiency
Bernard-Soulier syndrome (defect in platelet adhesion to von Willebrand factor)
Brain tumor (adults)
Supratentorial: metastasis > astrocytomoa (including glioblastoma multiform) > meningioma > schwannoma
Brain tumor (kids)
Infratentorial: medulloblastoma (cerebellum) or supratentorial: craniopharyngioma
Breast cancer
Infiltrating ductal carcinoma
Breast mass
Fibrocystic change, carcinoma (in post menopausal women)
Breast tumor (benign)
Fibroadenoma
Cardiac primary tumor (kids)
Rhabdomyoma, often seen in tuberous sclerosis
Cardiac manifestations of lupus
Libman-Sacks endocarditis (nonbacterial, affecting both sides of mitral valve)
Cardiac tumor (adults)
Metastasis, primary myxoma (4:1 left to right atrium; “ball and valve”_
Cerebellar tonsillar herniation
Chiari II malformation
Chronic arrhythmia
Atrial fibrillation (associated with high risk of emboli)
Chronic atrophic gastritis
Predisposition to gastric carcinoma (can also cause pernicious anemia)
Clear cell adenocarcinoma of the vagina
DES exposure in utero
Compression fracture
Osteoporosis (type I: postmenopausal woman; type II: elderly man or woman)
Congenital adrenal hyperplasia, hypotension
21-hydroxylase deficiency
Congenital cardiac anomaly
VSD
Congenital conjugated hyperbilirubinemia (black liber)
Dubin-Johnson syndrome
Constrictive pericarditis
TB (developing world); SLE (developed world)
Coronary artery involved in thrombosis
LAD>RCA>LCA
Cretinism
Iodine deficit/hypothyroidism
Cushing syndrome
- Iatrogenic Cushing (from corticosteroid therapy)
- Adrenocortical adenoma (secretes excess cortisol)
- ACTH-secreting pituitary adenoma
- Paraneoplastic Cushing (due to ACTH secretion by tumors)
Cyanosis (early; less common)
Tetralogy of Fallot, transposition of great vessels, truncus arteriosus
Cyanosis (late; more common)
VSD, ASD, PDA
Death in CML
Blast crisis
Death in SLE
Lupus nephropathy
Dementia
Alzheimer disease, multiple infarcts
Demyelinating disease in young women
Multiple sclerosis
DIC
Severe sepsis, obstetric complications, cancer, burns, trauma, major surgery
Dietary deficit
Iron
Diverticulum in pharynx
Zenker diverticulum (diagnosed by barium swallow)
Ejection click
Aortic/pulmonic stenosis
Esophageal cancer
Squamous cell carcinoma (worldwide); adenocarcinoma (US)
Food poisoning (exotoxin mediated)
S aureus, B cereus
Glomerulonephritis (adults)
Berger disease (IgA nephropathy)
Gynecologic malignancy
Endometrial carcinoma (most common in US); cervical carcinoma (most common worldwide)
Heart murmur, congenital
MVP
Heart valve in bacterial endocarditis
Mitral > aortic (rheumatic fever), tricuspid (IV drug abuse)
Helminth infection (US)
Enterobius vermicularis, Ascaris lumbricoides
Hematoma - epidural
Rupture of middle meningeal artery (trauma; lentiform shaped)
Hematoma - subdural
Rupture of bridging veins (crescent shaped)
Hemochromatosis
Multiple blood transfusions or hereditary HFE mutation (can result in CHF, “bronze diabetes,” and increased risk of HCC)
Hepatocellular carcinoma
Cirrhotic liver (associated with hep B and C and with alcoholism)
Hereditary bleeding disorder
von Willebrand disease
Hereditary harmless jaundice
Gilbert syndrome (benign congenital unconjugated hyperbilirubinemia)
HLA-B27
Ankylosing spondylitis, reactive arthritis, ulcerative colitis, psoriatic arthritis
HLA-DR3, DR4
Diabetes mellitus type 1, rheumatoid arthritis, SLE
Holosystolic murmur
VSD, tricuspid regurgitation, mitral regurgitation
Hypercoagulability, endothelial damage, blood stasis
Virchow triad (results in venous thrombosis)
Hypertension, secondary
Renal disease
Hypoparathyroidism
Accidental excision during thyroidectomy
Hypopituaritism
Pituitary adenoma (usually benign tumor)
Infection secondary to blood transfusion
Hep C
Infections in chromic granulomatous disease
Staph aureus, E coli, Aspergillus (catalase +)
Kidney stones
- Calcium - radiopaque
- Struvite (ammonium) - radiopaque (formed by urease + organisms such as Proteus vulgarism or Staph)
- Uric acid - radiolucent
Late cyanotic shunt (uncorrected left to right becomes right to left)
Eisenmenger syndroem (caused by ASD, VSD, PDA; results in pulmonary hypertension/polycythemia)
Liver disease
Alcoholic cirrhosis
Lysosomal storage disease
Gaucher disease
Male cancer
Prostatic carcionma
Malignancy associated with non infectious fever
Hodgkin lymphoma
Malignancy (kids)
ALL, medulloblastoma (cerebellum)
Metastases to bone
Prostate, breast > lung > thyroid
Metastases to brain
Lung > breast > GU > melanoma > GI
Metastases to liver
Colon»_space; stomach, pancreas
Mitochondrial inheritance
Disease occurs in both males and females, inherited through females only
Mitral valve stenosis
Rheumatic heart disease
Mixed (UMN and LMN) motor neuron disease
ALS
Nephrotic syndrome (kids)
Minimal change disease
Neuron migration failure
Kallmann syndrome (hypogonadotropic hypogonadism and anosmia)
Nosocomial pneumonia
Klebsiella, E coli, Pseduomonas aeruginosa
obstruction of male urinary tract
BPH
opening snap
mitral stenosis
opportunistic infection in AIDs
Pneumocystis jirovecii pneumonia
Osteomyelitis
S aureus
Osteomyelitis in sickle cell disease
Salmonella
Osteomyelitis with IV drug use
Pseudomonas, S aureus
Ovarian metastasis from gastric carcinoma or breast cancer
Krukenberg tumor (mucin-secreting signet-ring cells)
Ovarian tumor (benign, bilateral)
Serous cystadenoma
Ovarian tumor (malignant)
Serous cystadenocarcinoma
Pancreatitis (acute)
Gallstones, alcohol
Pancreatitis (chronic)
Alcohol (adults), cystic fibrosis (kids)
Patient with ALL/CLL/AML/CML
ALL: child
CLL: adult > 60
AML: adult ~ 65
CML: adult 30-60
PID
Chlamydia trachomatis,
Neisseria gonorrhoeae
Philadelphia chromosome t(9;22) (bcr-abl)
CML (may sometimes be associated with ALL/AML)
Pituitary tumor
Prolactinoma, somatotropic “acidophilic” adenoma
Primary amenorrhea
Turner syndrome (45,XO)
Primary bone tumor (adults)
Multiple myeloma
Primary hyperaldosteronism
Adenoma of adrenal cortex
Primary hyperparathyroidism
Adenomas, hyperplasia, carcinoma
Primary liver cancer
Hepatocellular carcinoma (chronic hepatitis, cirrhosis, hemochromatosis, alpha-1-antitrypsin deficiency)