2. Intro Bioinformatics

Question 1

Sensitivity

Answer 1

Find as many true positives as possible

Question 2

Specificity

Answer 2

predict as few false positives as possible

Question 3

Homology

Answer 3

a fundamental similarity based on common descent.

a structural similarity of two segments of one animal based on a common developmental origin

Question 4

Homologs can be either .. or ..

Answer 4

orthologs or paralogs

Question 5

Ortholog

Answer 5

ortho=exact, same exact gene in different organism

Question 6

Paralog

Answer 6

Paralogs are genes related by duplication within a genome. Orthologs retain the same function in the course of evolution, whereas paralogs evolve new functions, even if these are related to the original one.

Question 7

similarity

Answer 7

when looking at eg a sequene, two residues can be similar, eg not identical, but alike or often interchnaged from the other residue.

Question 8

Identity

Answer 8

degree to which two or more sequences are actually identical at each position