2-Gametogenesis Flashcards

1
Q

first phase of gametogenesis is identical in males and females,

A

whereas distinct differences exist between the male and female patterns in the last three phases.

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2
Q

Chromosomes

A

Carriers of genetic material

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3
Q

35000

A

On 46 chromosomes

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4
Q

Linked genes

A

Genes on the same chromosomes

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5
Q

Autosomes

A

22 pairs of matching chromosomes

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6
Q

One chromosome of each pair is derived from ___1___ and one from the ___2____

A

1- maternal gamete ( oocyte )

2- paternal gamete ( sperm )

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7
Q

Each gamete contain a haploid number of

A

23 chromosomes

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8
Q

Before entering mitosis each chromosome replicates its

A

DNA

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9
Q

Crossover

A

critical events in meiosis I- interchange of chromatid segments between paired homologous chromosomes

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10
Q

Genetic variability is enhanced through

A

Crossover and through random distribution

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11
Q

Numerous ooginia undergo

programmed degeneration

A

called atresia until menopause

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12
Q

Meiosis in Males

A

Begins after puberty

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13
Q

not all spermatogonia enter

A

meiosis at the same time unlike oogonia

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14
Q

When the spermatogonium enter the meiotic phase as primary spermatocyte

A

they spend several weeks dividing

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15
Q

DNA replication in Spermatogonium (type b)

A

Primary spermatocyte

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16
Q

First meiotic division ➡️

A

2 secondary spermatocytes

17
Q

Second meiotic division ➡️

A

4 spermatids

18
Q

Spermiogenesis ➡️

A

4 spermatozoa

haploid gametes

19
Q

meiotic divisions and result in four haploid spermatids takes

A

64 days

20
Q

acrosome

A

which covers half of the nuclear surface and contains enzymes to assist in fertilization

21
Q

Maturation of sperms

A
1- Formation of the acrosome
2- Condensation of the nucleus
3- Formation of the neck, middle piece,
and tail
4- Shedding of most of the cytoplasm as residual bodies
22
Q

Chromosomes fail to separate during meiosis, known as

A

nondisjunction

23
Q

General term for abnormal number of chromosomes in an embryo is termed

A

aneuploidy

24
Q

Down Syndrome

A

Trisomy 21

25
Q

Down syndrome

Symptoms and characteristics

A
  • delayed growth
  • distinct facial characteristics
  • intellectual disability
  • Premature aging
  • thyroid dysfunction
  • infections
26
Q

The risk of having a child with Down syndrome increases with

A

maternal age

27
Q

Trisomy 18

A
  • mental retardation
  • congenital heart defects
  • low set ears
  • flex ion of fingers and hands
28
Q

Trisomy 18 Incidence rate

A

1:5000

usually all die by 2 months of age

29
Q

Trisomy 13

A
  • cleft lip and palate
  • eye defects
  • deafness
  • mental retardation
    Incidence is 1/20,000

More than 90% die in their first month after birth

30
Q

Chromosome 13 in fluorescence

A

Green

31
Q

Chromosome 21 Fluorescence

A

Red