2) c) iii) Reversible Binding of Phosphate Flashcards

1
Q

addition or removal of a phosphate causes?

A

The addition or removal of phosphate can cause reversible conformational change in proteins

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2
Q

The addition or removal of a phosphate is?

A

This is a common form of post-translational modification

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3
Q

What enzyme is responsible for transfer of a phosphate to another protein

A

Protein kinases catalyse the transfer of a
phosphate group to other proteins

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4
Q
A

The terminal phosphate of ATP is transferred to specific R groups

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5
Q

What protein is responsible for the reverse reaction? What

A

Protein phosphatases catalyse the reverse reaction

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6
Q

What does phosphorylation do?

A

Phosphorylation brings about conformational changes, which can affect a protein’s activity

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7
Q
A

The activity of many cellular proteins, such as enzymes and receptors, is regulated in this way

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8
Q
A

Some proteins are activated by
phosphorylation while others are inhibited

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9
Q

addition of a phosphate adds what charge?

A

Adding a phosphate group adds negative
charges. Ionic interactions in the
unphosphorylated protein can be disrupted and new ones created.

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