2. Antiparasitários Flashcards

1
Q

Artesunato y artemeter lumefantrina son derivados de_

A

artemisina

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2
Q

Causan problemas GI, neurotoxicidad, urticaria, anafilaxis

A

Artesunato y artemeter

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3
Q

Se utiliza como primera línea para P. falciparum y para la Malaria/paludismo grave

A

Artesunato y artemeter

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4
Q

Mecanismo de acción de Cloroquina

A

Concentración en vacuolas y acumulación de complejos heme-heme cloroquina.

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5
Q

Causan prurito, prolongan QT, neurotoxicidad, maculopatía

A

Cloroquina

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6
Q

De elección para malaria/paludismo y alternativa profilaxis en áreas sensibles

A

Cloroquina

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7
Q

La cloroquina tiene resistencia a _

A

falciparum y vivax

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8
Q

R a _ se asocia a mayor S a mefloquina

A

cloroquina

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9
Q

Causa GI, exantema, neuropsiquiatricos

A

Mefloquina

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10
Q

La mefloquina tiene un incremento de amplificación de_

A

pfndr1

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11
Q

Inhibe digestión de hemoglobina y ATPasa

A

Quinina/Quinidina

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12
Q

Para Plasmodium spp., babesia

A

Quinina/Quinidina

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13
Q

Causa RAM cardiovascular, Hipoglucemia, Cinconismo

A

Quinina/Quinidina

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14
Q

La quinina tiene una resistencia cruzada con_

A

mefloquina

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15
Q

De elección en Plasmodium spp. En especial por P. vivax y P. ovale (hipnozoítos)

A

Primaquina

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16
Q

Se usa en malaria/paludismo y profilaxis por P. vivax y p. ovale.

A

Primaquina

17
Q

Causa RAM GI, cefalea, debilidad, prurito, alteraciones visuales, hemólisis en deficiencia de G6PD, metahemoglobinemia

A

Primaquina