1st year buzzwords Flashcards
Ig found in mucosa
IgA
what produces endotoxin
gram negative
what produces exotoxin
gram positive
Ig found in breast milk
IgA
Ig assoc. hypersensitivity
IgE
what receptors does IgE bind to
Fc receptors
most common time of Ig
IgG
first antibody to appear in response to an antigen
IgM
trachea palpated
suprasternal notch/jugular notch
nerve that supplies the rectum
S4/inferior rectal nerve (S2 3 4 pudendal)
nerve that supplies the diaphragm
C3 4 5/phrenic nerve
what is the inheritance of CF
AR
bone has no other articulations
hyoid
2,3-DPG does what
acid that helps bind O2. reduced amounts of it results in more dissociation
cranial nerves sensory motor or both
Some Say Money Matters But My Brother Says Big Boobs Matter More
jugular foramina
Carlos Only Smokes Spliff Since Rastaman Offered Skunk In Indigenous Jamaica Jamaican Joint Heaven
parasympathetic cranial nerves
III
VII
IX
X
sympathetic outflow
T1 - L2
stony dull to percuss
pleural effusion
right sided pleuritic chest pain
most likely pneumonia
alveolar bats wings kerley B lines cardiomegaly dilated prominent upper lobe vessels pleural effusion
pulmonary oedema
ground glass appearance on Xray
pulmonary fibrosis and respiratory distress syndrome of the newborn
Ziehl neelsen stain positive for acid fast bacilli
TB
caseous necrosis
TB
apical disease
most likely secondary TB
apical lesion in TB is called an
Assman focus
Miliary TB
spread of organism into blood stream
if TB spreads via pulmonary artery miliary disemination into the…
lung occurs
if TB spreads via pulmonary vein….
systemic dissemination to liver spleen and kidneys
positive anti-glomerular basement membrane antibodies
Goodpastures syndrome
chest infection with parrot/pigeon as a pet
chlamydophila psittaci
dry cough and diarrhoea after holiday abroad/water spread
legionella pneumophila (test urine for antigens)
tall thin young man who indulges in marijuana
pneumothorax (marfans)
bilateral hilar lymphadenopathy erythema nodosum granulomas fatigue uveitis weight loss
sarcoidosis
bronchiole wider than neighbouring arteriole on CT (signet ring sign)
bronchiectasis
D sign on x ray
empyema
steeple sign on X ray
laryngotracheobronchitis/croup
child with a barking cough
croup
pneumocystis pneumonia
HIV
tx: co-trimoxazole
Samter’s triad
Asthma + nasal polyps + salicylate sensitivity
Alcoholic (danger of aspiration pneumonia)
klebsiella pneumonia
red jelly sputum
klebsiella pneumonia
mucoid sputum
chlamydia psitttaci
rusty sputum
pneumococcal pneumonia
cannon ball mets
weight loss
haematuria
from primary renal cell carcinoma
morning headache
hypercapnia or side effect or organic nitrate
ACTH secreting lung tumour
small cell carcinoma of the lung
PTH secreting tumour of the lung
squamous cell carcinoma
increased serum ACE and Ca2+
Sarcoid
eggshell calcification at hilar region
silicosis
heart failure cells seen in alveolar spaces
macrophages that have absorbed haemosiderin - found in chronic pulmonary oedema and associated severe left ventricular heart failure.
also seen in long standing pulmonary hypertension
ghon focus
TB
area of infection and caseous necrosis at periphery of lung beneath the pleura
ghon focus rupture
tuberculous pleurisy
coin lesion on chest radiograph
rounded solitary lesion - primary bronchial or lung carcinoma, metastatic tumour (esp. of kidney), bronchial hamartoma, carcinoid tumour, granulomatous inflammation, lung abscess
ptosis
enopthalmos
miosis
anhydrosis
horners syndrome
- invasion of cervical sympathetic chain
horners syndrome
pancoast tumour
acute management of asthma
OSHITMAN Oxygen Salbutamol Hydrocortisone Ipratropium Theophylline Magnesium Anaesthetist
thumbprint sign on head xray
epiglottitis
inspiratory whoop / barking cough
pertusis
snow storm appearance on xray
baritosis/silicosis
infective exac of COPD
iSOAP ipratropium salbutamol oxygen amoxicillin prednisolone
non smoker and lung cancer
peripheral adenocarcinoma
squamous and small cell lung cancers
central
high d dimer
suspect PE
suspect PE
CTPA or V/Q scan
low d dimers
exclude PE
large PE
thrombolysis
small PE
LMWH
respiratory alkalosis
panic attack
frank pus on aspiration
empyema
obstructive lung disease and raised eosinophils
asthma
obstructive lung disease and raised neutrophils
COPD
Pickwickian disease a.k.a. obesity hypoventilation syndrome
obese people whose body fat is preventing air getting in - sleep apnoea and hypercapnia - OVERNIGHT NASAL VENTILATION
guillian barre disease causes
paralysis
guillian barre is normally preceded by
normally preceded by strep infection of resp or GI tract
gullian barre paralysis begins where and moves where
begins in feeet and ascends to other muscles
what causes guillian barre
antibodies bind to peripheral nerve glycoprotein
coal workers pneumoconiosis - 2 types
simple coal workers pneumoconiosis and progressive massive fibrosis - later form
coal workers pneumoconiosis problems found
apex of the lung
adult respiratory distress syndrome
occurs when non-cardiogenic pulmonary oedema leads to acute resp failure
adult respiratory distress syndrome CXR
bilateral alveolar shadowing
pulmonary oedema CXR
bats wings - perihilar shadowing
upper lobe venous diversion
fluid in horizontal fissure
Kerley B lines
TLCO
how well oxygen can diffuse into blood
asthma and COPD do what to TLCO
preserved
TLCO in anaemia, emphysema, interstitial lung disease, pneumonia, pulmonary oedema, pulmonary emboli, bronchiectasis do what to TLCO
decreased
polycythaemia does what to TLCO
increased
asbestosis
problem in base of lung
22 yo woman weight loss sputum night sweats tender well defined nodules on shins bilaterally
erythema nodosum
extrinsic allergic alveolitis
granulomatous inflammation of the lungs
extrinsic allergic alveolitis acute causes
pneumonitis
extrinsic allergic alveolitis chronic causes
fibrosis and emphysema
extrinsic allergic alveolitis tx
steroids and antigen avoidance
extrinsic allergic alveolitis CXR
bilateral reticulonodular shadows
extrinsic allergic alveolitis “farmers lung”
major antigen is saccharopolyspora rectivirgula
lymphocytes
extrinsic allergic alveolitis “bird fanciers lung”
avian proteins - pigeons, parrots
exudate
protein > 30
transudate
protein < 30
most common lung type in smokers
squamous cell
squamous cell carcinoma of lung secretes
PTH causing hypercalcaemia
smoker
cavitating
hilar tumours
squamous cell carcinoma of lung
large cell tumour of lung
poorly differentiated
sex hormone releasing - gynaecomastia
lung cancer in non smokers
adenocarcinoma
adenocarcinoma mucus stains
blue
adenocarcinoma of lung causes
hypertrophic pulmonary oesteoarthropathy - finger clubbing, periosteal inflammation (like ankle pain)
worst prognosis of lung cancers
small cell
lung cancer that is chemo sensitive
small cell
small cell lung cancer secretes
ADH causing SIADH
or ACTH causing cushings
pancoast tumour
apex of lung
brachial plexus lesions cause
finger tingling
arm pain
asthma is an
obstructive airway disease
COPD is an
obstructive airway disease
spirometry in asthma
FVC normal
FEV1 reduced
FEV1/FVC ratio reduced
COPD spirometry
FVC reduced
FEV1 reduced
FEV1/FVC normal
restrictive airway disease spirometry
FVC reduced
FEV1 reduced
FEV1/FVC ratio normal
normal
reduced
> 75%
< 75%
respiratory failure type 1
low oxygen levels
respiratory failure type 2
low oxygen levels and high carbon dioxide levels e.g. COPD
TB drugs
2 RIPE 4 RI
middle ages asian weight loss night sweats productive cough CXR multiple small discrete nodules throughout both lung fields
TB
TB drug that causes red orange discolouration of urine and tears
rashes
hepatotoxicity
rifampicin
TB drug that causes tingling / paraesthesia of the extremities
isoniazide
TB drug that causes joint pain, rash, allergic reaction, yellow skin or eyes, worsening gout
Pyrazinamide
TB drug that causes change in vision, optic neuritis, red green colour blindness
ethambutol
TB is what HSR
type 4
TB is a __ cell response to _____
T cell response to mycobacterial infection
m. tuberculosis
m. bovis
M. africanum
primary TB
small focus - Ghon focus, large hilar granulomatous nodes
secondary TB
fibrosing cavitating apical lesion - immunosuppression
head ache
mucoid sputum
chlamydophilia psittaci (birds)
coxiella burnetti
sheep/farm/Q fever
urine antigen test
GI upset
water foreign holiday
legionella
dry cough/young people pneumonia
mycoplasma
pneumocystis carinii pneumonia
HIV AIDS immunosuppressed
rusty sputum
strep pneumonia - usually lobar pneumonia
CF patients pneumonia
staph aureus
pseudomonas aeruginosa
COPD/alcoholics/elderly
H. influenza
Klebsiella (red jelly sputum)
bordetella pertusis
whooping cough/bronchopneumonia
pseudomonas aeruginosa
CF, UTI, GI, Burns, Scars - gram negative bacillus
causes of pulmonary fibrosis
BREAST CA
bleomycin, radiation, extrinsic allergic alveolitis, ank spond, sarcoidosis, TB, crytogenic fibrosing alveolitis (idiopathic pulmonary fibrosis) asbestosis
causes or erythema nodosum
NODOSUM backwards Mycobacterium (TB) UC/Crohns Sarcoidosis Other infections (strep, mycoplasma, EBV) Drugs (sulphonamides, OCP) Occult malignancy No cause/Nurturing (pregnant)
fever and pleuritic chest pain relieved on sitting up and leaning forward
pericarditis
irregularly irregular pulse
AF
ECG saw tooth baseline + 150 bpm
atrial flutter
raised JVP/hepatojugular reflex
right sided heart failure
sense of impending doom
MI
saddle shaped ST elevation
pericarditis
broad complex tachycardia
ventricular problem
mid-diastolic murmur with a tapping undisplaced apex
mitral stenosis
broad QRS with slurred upstroke on R wave (delta wave)
wolff-parkinson white syndrome
tall tented T waves
wide QRS
hyperkalaemia
pericarditis 4-6 weeks post MI
dresslers syndrome
blurred yellow vision headache
digoxin toxicity
janeway lesions/osler nodes
subacute bacterial endocarditis
continuous machine like murmur
patent ductus arteriosus
rib notching on CXR
coarctation of aorta
crescendo decrescendo murmur
aortic stenosis
diminished absent lower limb pulses
coarctation of aorta
MRS ASS
mitral regurgitation systolic
aortic stenosis systolic
ACEI side effect and CI
dry cough
bilateral renal artery stenosis
radial radial delay
aortic dissection
coarctation of aorta
collapsing pulse
aortic regurgitation
slow rising pulse
aortic stenosis
spinter haemorrhages
infective endocarditis
endocarditis cause with prosthetic valves or IV drug users
staph aureus
present in mouth after dental surgery
strep viridans
what is an atrial myxoma
non cancerous tumour in the upper left or right side of heart - most often grows on wall that separates 2 sides of heart
cardiac tamponade
collection of blood / fluid / pus etc around the heart in the pericardial space preventing contractions
treatment of pericarditis
pain relief - NSAIDs
tetralogy of fallot
large ventricular septal defect
overriding aorta
right ventricular outflow obstruction (pulmonary stenosis)
right ventricular hypertrophy
wide pulse pressure
aortic regurgitation aortic dissection complete heart block thyrotoxicosis persistent doctor arterioles
acute limb ischaemia 6 Ps
pale pulseless painful paralysed paraesthetic perishingly cold
tx of shock
ABCDE oxygen fluids inotropes - cardiogenic chest drain - obstructive vasopressors - septic adrenaline - anaphylaxis
gingival hypertrophy/gingivectomy/biting own gums
side effect of calcium channel blockers or phenytoin
bird beak appearance and distended oesophagus
achalasia
or if in lower GI imaging - bowel obstruction
grey turners sign
cullens sign
grey turners - lumbar redness
cullens sign - umbilical redness
acute pancreatitis
murphy sign positive
cholecystitis
pale stools
jaundice
abdo pain
biliary obstruction
abdo distension
caput medusae
shifting dullness
portal hypertension + ascites
pyoderma gangrenosum/erythema nodosum
crohn’s/UC
tinkling bowel sounds
bowel obstruction
vesicular rash + weight loss
coeliac disease
virchows node
left supraclavicular node
gastric cancer
urea breath test
h. pylori
14C breath test
bacterial overgrowth
rice water like stools
vibrio cholera
primary biliary cirrhosis
AMA (anti-mitochondrial antibodies)
autoimmune hepatitis
ASMA (anti smooth muscle antibodies)
alpha feto protein assay
hepatocellular carcinoma or teratoma
cobble stone mucosa
deep fisuring ulceration of mucosa - crohns disease
tx for ascites
spironolactone
corkscrew oesophagus on barium swallow
diffuse oesophageal spasm
severe abdo pain and D+V after raw milk
campylobacter
russels sign
self induced vomiting
mallory’s hyaline bodies
alcoholic liver disease (acute hepatitis) / chronic active hepatits
crypt abscess/crypitits
crohns
onion skinning fibrosis
beading of bile ducts
primary sclerosing cholangitis
signet ring cells seen on biopsy
linitis plastica - diffuse stomach cancer
thumb printing on Xray commonly at splenic flexure
ischaemic colitis
charcots triad
acute cholangitis - fever, jaundice and abdopain secondary to cholelithiasis
mouth disease in crohns
stomatitis gangrenosum
replacement of oesophageal stratified squamous epithelium by simple columnar epithelium and goblet cells
barretts oesophagus/pre cancer
dukes classification
A - confined to bowel wall
B - local spread outwith bowel wall
C - lymph node mets
AST is raised in
alcoholic liver disease
wASTed
is ALT or AST more specific to the liver
ALT
causes of abdo distension 6 Fs
fat foetus flatus faeces fluid fucking massive tumour