1st Six Weeks Flashcards
Functional groups
-Hydroxyl (-OH)
-Sulfhydryl (-SH)
-Carboxyl (-COOH or -COO-)
-Animo (-NH2 or NH3+)
Phosphate (-PO4)
-Methyl (-CH3)
Common Molecules
-Ribose
-Deoxyribose
-Glucose
-Polymers of glucose may be starch, chitin,
glycogen, etc. depending on bonding
arrangement. No need to be able to
decipher between them.
-Glycerol
-Saturated fat
-Unsaturated fat
-Cholesterol
-ATP
-DNA components: Purine, Pyrimidine, Deoxyribose (including 5’ and 3’ carbon notation)
-Phosphate: Bonds (hydrogen, phosphodiester, covalent)
-Amino acid structure
-Hemoglobin
Element
each of more than one hundred substances that cannot be chemically interconverted or broken down into simpler substances and are primary constituents of matter. Each element is distinguished by its atomic number, i.e., the number of protons in the nuclei of its atoms.
Atomic number
the number of protons in the nucleus of an atom, which determines the chemical properties of an element and its place in the periodic table.
Atomic mass
the mass of an atom of a chemical element expressed in atomic mass units. It is approximately equivalent to the number of protons and neutrons in the atom (the mass number) or to the average number allowing for the relative abundances of different isotopes.
Atoms and Bonding
The nucleus consists of protons and neutrons. Electrons are found in general areas with general shapes. These areas are called electron clouds. In addition, electron energy can measured as a distance from the nucleus. Energy levels and electron orbitals overlap. It is therefore possible that two electrons be at different energy levels while occupying the same orbital. The valence electrons are most significant as they are involved in bonding.
Carbohydrates
any of a large group of organic compounds occurring in foods and living tissues and including sugars, starch, and cellulose. They contain hydrogen and oxygen in the same ratio as water (2:1) and typically can be broken down to release energy in the animal body.
“water-soluble carbohydrates”
Lipids
any of a class of organic compounds that are fatty acids or their derivatives and are insoluble in water but soluble in organic solvents. They include many natural oils, waxes, and steroids.
Nucleic Acids
a complex organic substance present in living cells, especially DNA or RNA, whose molecules consist of many nucleotides linked in a long chain.
Protein
any of a class of nitrogenous organic compounds that consist of large molecules composed of one or more long chains of amino acids and are an essential part of all living organisms, especially as structural components of body tissues such as muscle, hair, collagen, etc., and as enzymes and antibodies. proteins collectively, especially as a dietary component.
Exergonic vs. Exergonic
- Exergonic: (of a metabolic or chemical process) accompanied by the release of energy.
- Endergonic: (of a metabolic or chemical process) accompanied by or requiring the absorption of energy, the products being of greater free energy than the reactants
Glycolysis
- The initial metabolic pathway of cellular respiration in which a series of reactions happening in the cytosol results in the conversion of a monosaccharide, often glucose, into pyruvic acid, and the concomitant production of a relatively small amount of high-energy molecules, such as ATP.
- The cellular degradation of the simple sugar, glucose, to yield ATP as an energy source.
ATP
- Abbreviation for adenosine triphosphate, empirical formula: C10H16N5O13P3
- An organic compound composed of adenosine (an adenine ring and a ribose sugar) and three phosphate groups, hence, the name.
- Supplement: ATP is a nucleotide that contains a large amount of chemical energy stored in its high-energy phosphate bonds. It releases energy when it is broken down (hydrolyzed) into ADP (or Adenosine Diphosphate). The energy is used for many metabolic processes. Hence, ATP is considered as the universal energy currency for metabolism. ATP is produced via cellular respiration in the mitochondria and photosynthesis in chloroplasts. Its functions are for intracellular energy transport for various metabolic processes including biosynthetic reactions, motility, and cell division. It is also used as a substrate by kinases that phosphorylate proteins and lipids, and by adenylate cyclase to produce cyclic AMP.
Cellular Respiration: Step 1 - Glycolysis
- Activation energy input: The cell uses 2 molecules of ATP as activation energy to rearrange the glucose molecule into another 6-carbon molecule called fructose diphosphate (aka fructose biphosphate) which can be split into two 3-carbon molecules
- Splitting the fructose: The fructose biphosphate can be split into two 3-carbon molecules of PGAL (G-3-P). Energy can be harvested easily from PGAL.
- Harvesting the energy: The energy is captured:
- 2 molecules of ADP are used to create 2 molecules of 2 ATP. This is referred to as substrate level phosphorylation
- 2 more ADP and 2 NAD+ molecules are used to make 2 molecules of NADH and 2 additional molecules of ATP
- 2 pyruvate (pyruvic acid) molecules remain, and these pyruvate molecules contain most of the original energy that was present in the original glucose molecule. The purpose of aerobic cellular respiration is to harvest as much of the energy in the two 3-carbon pyruvate molecules as possible.
Cellular Respiration- Glycolysis Summary
Glyco- (sugar or glucose) and -lysis (break down). Glycolysis does not require oxygen, it occurs in the cytoplasm of the cell, and it’s the one metabolic pathway that is found in all living organisms. Four molecules of ATP are produced in glycolysis, but two ATP must be used in the activation energy input. The net yield is only 2 ATPs. If oxygen is not present, anaerobic fermentation reactions allow glycolysis to continue to produce ATP by recycling NADH to NAD+.
Oxidation
Any chemical reaction in which a material gives up electrons, as when the material combines with oxygen
O.I.L. : Oxidation is Losing
Reduction
Any chemical reaction in which the atoms in a material take on electrons. Note: Reduction is the opposite of oxidation.
R.I.G.: Reduction is Gaining
Cellular Respiration
The chemical process that generates most of the energy in the cell, supplying molecules needed to make the metabolic reactions (see metabolism) of an organism run. Note: The main carrier of energy in metabolism is the molecule ATP.
Reaction
Substrate molecule binds with active site of enzyme molecule; Reaction occurs and product molecules are generated
Inhibition
Inhibitor molecules bind with active site of the enzyme molecule; Inhibitor molecule prevents the binding of substrate molecule
Electrons
THEY HAVE POTENTIAL ENERGY, regardless of charge.
Reducing agent vs. Oxidizing Agent
Electron donor and Electron receiver (i.e. Oxygen)
Electronegative
containing negative electricity; tending to migrate to the positive pole in electrolysis.
assuming negative potential when in contact with a dissimilar substance.
More electronegative = loses potential energy
Oxidation of organic compounds
Breaking down
Molecular Oxygen
O2 takes in electrons (electronegative)
C6H12O6 -> C6H11O6
Glucose becomes oxidized. The hydrogen was lost because of the electrons due to the oxidation-reduction.