1B- more biological Molecules Flashcards
DNA purpose ?
Store genetic information- instructions to grow and develop
RNA purpose ?
transfers genetic information to the ribosomes
Ribosomes made of
RNA and proteins
Nucleotide
monomers that make up polynucleotides- phosphate group, pentose sugar and nitrogen containing base
Polynucleotide structure
-Nucleotide join via condensation reactions between phosphate of one and pentose sugar of other forming phosphodiester bond
-sugar phosphate backbone
-
phosphodiester bond
bond between pentose sugar and phosphate
DNA structure
1-double helix of 2 twisted anti-parallel polynucleotide strands held by H Bonds between specific complementry nitrogen containing base pairs
2-deoxyribose sugar
3-thymine
4-long polynucleotide strands
RNA structure
1- single polynucleotide strand
2-ribose
3-uracil
4-short polynucleotide stand
AT and CG number of bonds
AT=2
CG=3
direction of strand in DNA
antiparallel
how to form phosphodiester bonds
condensation reations release a water molecule and links together
DNA semi conservative replication
1-DNA Helicase breaks H bonds between complementary bases on 2 polynucleotide strands and double helix unwinds
2-free floating DNA nucleotides are attracted to exposed complementary base pairs on template strand
3-condenation reactions join nucleotides together via phosphodiester bonds catalysed by DNA polymerase. 4- H Bonds between bases on new and template join foaming 2 DNA strands
Purpose of DNA semi conservative replication
ensure genetic continuity between generations of cells
Action of DNA polymerase
- Active site of DNA polymerase complementry to 3 Prime (OH) end of newly forming DNA strand
- 5 to 3 direction on new strand
- DNA polymerase work on template strands in opposite directions due to antiparallel strands
Direction of DNA polymerase
New strand- 5 to 3
Template strand- 3 to 5