1b// Arterial blood gases + acid base regulation Flashcards
what is pulmonary transit time?
amount of time erythrocytes and plasma are in contact and able to undergo gas exchange
what is gas exchange time?
amount of time for CO2 and O2 to equilibrate
how do you calculate H+ concentration from pH?
10^-pH
how do you calculate pH from H+ concentration?
-log10(H+)
what is an acid?
any molecule with a loosely bound H+ that it can donate
what is the body’s acid base equilibrium?
H2O + CO2 = H+ + HCO3-
what is the body’s method for rapid compensation of pH imbalances?
respiratory - ventilation changes
what is the body’s method for slow compensation of pH?
metabolic - HCO3- or H+ retention/secretion changes in the kidney
what is an acidosis?
low pH in the body
what are the steps for interpreting an ABG?
type of pH imbalance
aetiology of imbalance
any compensation
oxygenation
what are the pH ranges for the body?
high - >7.45
normal - 7.35-7.45
low - <7.35
what are the CO2 ranges of the body?
low <4.7kPa
normal 4.7-6.4 kPa
high >6.4kPa
what are the body ranges for base excess?
low 2
what are the normal oxygen ranges?
hypoxemia <10kPa
normal 10-13.5kPa
hyperoxemia >13.5kPa
how do you know if an ABG is mixed or partially compensated?
mixed - PCO2 and BE going in OPPOSITE directions
partially compensated - PCO2 and BE going in SAME direction