1A - Innate Immunity Flashcards

1
Q

infectious diseases are caused by

A

Bacteria, Virus, Prions, Protozoa, Fungi, Parasites

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2
Q

non-infectious diseases are caused by

A

Nutritional, metabolic, trauma, toxic materials, congenital defects

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3
Q

a contagious disease

A

Animal to animal transfer

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4
Q

noncontagous disease

A

Environment to animal transfer

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5
Q

the infectious disease process

A

◦ Enter host (invade) ◦ Multiply ◦ Evade host (hide) ◦ Harm host

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6
Q

the determinants of disease (triad of disease determinants)

A

Host, Agent, Environment

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7
Q

Host (determinants of disease)

A

genotype, species, breed, age, sex, social and occupational factors

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8
Q

Agent (determinants of disease)

A

Pathogenicity and virulence

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9
Q

Environment (determinants of disease)

A

location, climate, housing, management, feeding, stress

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10
Q

portals of entry (of pathogens)

A

Ingestion, Inhalation, Cutaneous penetration, Ascending infection

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11
Q

direct transmission

A

cough, touch, bites, grooming, licking, ingestion

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12
Q

vector

A

organisms that transmit an infectious agent from one animal to another

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13
Q

fomites

A

inanimate objects that transmit a particular disease or parasite from one animal to another

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14
Q

indirect transmission

A

transmission via vector or fomite

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15
Q

epidemic

A

rate of new cases in a population is greater than expected

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16
Q

endemic

A

disease is maintained at a relatively constant rate in the population without the need for external input

17
Q

pandemic

A

epidemic of worldwide distribution

18
Q

classification of disease by spread

A

transmission

19
Q

commensalism

A

relationship in which neither parties are harmed

20
Q

mutualism

A

relationship in which both benefit

21
Q

parasitism

A

relationship in which one lives at the expens of other

22
Q

virulence and pathogenicity can be used to describe

A

the ability of the agent to cause disease; used interchangably

23
Q

virulence

A

the degree of harm the organism causes

24
Q

pathogenicity

A

refers to the ability of an organism to cause disease

25
Q

infectious dose

A

minimum number of organisms required to cause infection

26
Q

factors that effect infectious dose

A

age, sex, immune status, pregnancy status

27
Q

types of pathogens

A

obligate, opportunistic

28
Q

obligate pathogens

A

associated only with disease

29
Q

opportunistic pathogens

A

potential pathogens; part of the norma flora until oportunity strikes via host becoming immunocompromised

30
Q

frontal assault pathogenic microbes

A

(acute)‣ Short incubation ‣ Rapid clinical signs ‣ Intimate transmission ‣ Ex - many childhood diseases, parvovirus in dogs, salmonellosis, acute mastitis, COVID

31
Q

stealth assault pathogenic microbes

A

(insidious) ‣ Incubation lengthy ‣ Slow onset of signs ‣ May have environmental transmission ‣ Ex - Bovine Johne’s Disease, Tuberculosis, Chronic wasting disease

32
Q

host

A

describe the lifecycle of hlminths and protozoa

33
Q

definitive host

A

in which the infectious agent reaches sexual maturity or replicates

34
Q

intermediate host

A

essential part of the parasite lifecycle; temporary environment for development

35
Q

reservoir host

A

harbors pathogens that infect others; host does not demonstrate clinical signs of the disease

36
Q

dead-end host

A

can get infected but is unlikely to pass the agent to another host