1A - Innate Immunity Flashcards

1
Q

infectious diseases are caused by

A

Bacteria, Virus, Prions, Protozoa, Fungi, Parasites

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2
Q

non-infectious diseases are caused by

A

Nutritional, metabolic, trauma, toxic materials, congenital defects

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3
Q

a contagious disease

A

Animal to animal transfer

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4
Q

noncontagous disease

A

Environment to animal transfer

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5
Q

the infectious disease process

A

◦ Enter host (invade) ◦ Multiply ◦ Evade host (hide) ◦ Harm host

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6
Q

the determinants of disease (triad of disease determinants)

A

Host, Agent, Environment

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7
Q

Host (determinants of disease)

A

genotype, species, breed, age, sex, social and occupational factors

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8
Q

Agent (determinants of disease)

A

Pathogenicity and virulence

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9
Q

Environment (determinants of disease)

A

location, climate, housing, management, feeding, stress

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10
Q

portals of entry (of pathogens)

A

Ingestion, Inhalation, Cutaneous penetration, Ascending infection

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11
Q

direct transmission

A

cough, touch, bites, grooming, licking, ingestion

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12
Q

vector

A

organisms that transmit an infectious agent from one animal to another

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13
Q

fomites

A

inanimate objects that transmit a particular disease or parasite from one animal to another

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14
Q

indirect transmission

A

transmission via vector or fomite

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15
Q

epidemic

A

rate of new cases in a population is greater than expected

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16
Q

endemic

A

disease is maintained at a relatively constant rate in the population without the need for external input

17
Q

pandemic

A

epidemic of worldwide distribution

18
Q

classification of disease by spread

A

transmission

19
Q

commensalism

A

relationship in which neither parties are harmed

20
Q

mutualism

A

relationship in which both benefit

21
Q

parasitism

A

relationship in which one lives at the expens of other

22
Q

virulence and pathogenicity can be used to describe

A

the ability of the agent to cause disease; used interchangably

23
Q

virulence

A

the degree of harm the organism causes

24
Q

pathogenicity

A

refers to the ability of an organism to cause disease

25
infectious dose
minimum number of organisms required to cause infection
26
factors that effect infectious dose
age, sex, immune status, pregnancy status
27
types of pathogens
obligate, opportunistic
28
obligate pathogens
associated only with disease
29
opportunistic pathogens
potential pathogens; part of the norma flora until oportunity strikes via host becoming immunocompromised
30
frontal assault pathogenic microbes
(acute)‣ Short incubation ‣ Rapid clinical signs ‣ Intimate transmission ‣ Ex - many childhood diseases, parvovirus in dogs, salmonellosis, acute mastitis, COVID
31
stealth assault pathogenic microbes
(insidious) ‣ Incubation lengthy ‣ Slow onset of signs ‣ May have environmental transmission ‣ Ex - Bovine Johne's Disease, Tuberculosis, Chronic wasting disease
32
host
describe the lifecycle of hlminths and protozoa
33
definitive host
in which the infectious agent reaches sexual maturity or replicates
34
intermediate host
essential part of the parasite lifecycle; temporary environment for development
35
reservoir host
harbors pathogens that infect others; host does not demonstrate clinical signs of the disease
36
dead-end host
can get infected but is unlikely to pass the agent to another host