19 - 3 Parent Babies Flashcards
1
Q
What is the theory explaining mitochondria in cells?
A
Endosymbiotic theory
2
Q
What are clinical presentations of mitochondrial disease?
A
- Weakness
- Fatigue
- Spasms and seizures
- Inability to put weight on
- Hearing loss
- Elevated lactate
- Autism
- Developmental delay
3
Q
What are the features of a family history of mitochondrial disease?
A
- Similar pattern to autosomal recessive
- Look at maternal line
4
Q
Why are some people affected more by mitochondrial disease?
A
- Different ratios of healthy to faulty mitochondria
- Depending on how meiosis occur, the number of mitochondria in each gamete varies
5
Q
What is the prognosis for mitochondrial disease?
A
- Progressive weakness
- Death
- Flares up and down
6
Q
What are the five ethical approaches and what is an ethical framework?
A
7
Q
What are ethical issues involved with three parent babies?
A
8
Q
What are the two ways of carrying out 3 parent babies?
A
- Has to be done in proper IVF lab
- Has to be developed here or people will want to go to other countries to do it
