18.1Glycolysis

Question 1

What happens in glycolysis

Answer 1

first step of respiration

glucose broken down into pyruvate

releasing ATP (net 2) & NADH (2).

common to both aerobic & anaerobic.

Question 2

Outline the process of glycolysis

Answer 2

Glucose is phosphorylated to 2 x triose phosphate this uses 2 Pi so 2 ATP —-> 2 ADP (hexose bisphosphate is the intermediate but its unstable to breaks down to 2 TP)
2TP are then dehydrogenated and dephosphorylated to produce 2 pyruvate this reduces 2 NAD (coenzyme) and forms 4 ATP

Some overall net gain is 2 ATP & 2 NADH

Question 3

Why type of phosphorylation is glycolysis an example of?

Answer 3

Substrate level phosphorylation

Question 4

What is substrate level phosphorylation

Answer 4

The formation of ATP without the involvement of electron transport chain

Question 5

How does NAD act as a coenzyme in glycolysis

Answer 5

transfers atoms from 1 reaction to another in a multi-step pathway:

NAD accepts hydrogen atom from dehydrogenation of triose bisphosphate & is reduced

supplies hydrogen atom to enzyme involved in later stage of respiration

Question 6

Where does glycolysis occur

Answer 6

In the cytoplasm