1.8 Genomic Sequencing Flashcards
What are computer programmes used to do in genomic sequencing?
Computer programmes can be used to identify base sequences by looking for sequences similar to known genes
What is required to compare sequence data?
Bioinformatics are needed to compare sequence data
Why are genomes sequenced?
Many disease causing organisms and pest species have their genomes sequenced as they are important model organisms for research
What is phylogenetics?
Phylogenetics is the study of evolutionary and history relationships
Why is sequence data used?
Sequence data is used to study the evolutionary relatedness among groups of organisms
Why is sequence divergence used?
Sequenced divergence is used to estimate time since lineages diverged
What can differences in sequence data indicate?
Differences in sequence data can indicate time of divergence from a common ancestor
What is a molecular clock?
Molecular clocks are used to show when species diverged during evolution
What do molecular clocks assume?
Molecular clocks assume a constant mutation rate and show difference ps in DNA sequences or amino acid sequences
What is pharmacogenetics?
Pharmacogenetics is the use of genome information in the choice of drugs
What can an individual’s personal genome be used to select?
The most effective drugs and dosage to treat their disease (personalised medicine)
