1.6 Immunity Flashcards
Phagocytosis
Phagocyte attracted by chemoattractants, binds, lysosomes migrate and release enzymes, breakdown products absorbed
Non specific defence mechanisms
Barriers and phagocytosis
Monoclonal antibodies
Grown outside body to target one specific antigen, mouse creates B cells, polyclonal cells extracted, separated, cultured, cloned
Passive vaccines
Antibodies given from outside source (short lived)
Active vaccines
Stimulation of own immunity (long lasting)
Pro and cons of vaccines
Side effects, trained staff, herd immunity, defective immunity, mutations, disease develops too soon, HIV, travel
Antibody
Light and heavy chains, variable and constant regions, receptor and antigen binding sites…..quaternary
T lymphocyte
Thymus gland, cell mediated
Respond to antigen presenting cells, mitosis
Memory, B cell, phagocytes, holes
B lymphocyte
Bone marrow, humoral
Process antigen, present them, mitosis
Plasma(primary), memory(secondary)