16 ENF INTESTINAL Flashcards

1
Q

ENF DE CROHN

DEFINICION

A

TRASTORNO INFLAMATORIO CRONICO QUE PUEDE INVOLUCRAR CALQUIERE parte del tracto instetinal desde la boca hasta el ano generando lesiones TRANSMURALES discontinuas

chron todo

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2
Q

LOCALIZACION FC

ENF CROHN

A

ILEON TERMINAL Y COLON DERECHO

(union ileocecal)

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3
Q

FACTORES PROTECTORES

ENF DE CROHN

A
  • Dieta rica en zinc (disminuye el riesgo hasta 40%)
  • uso de estatinas
  • menor incidencia en raza hispana y en zonas rurales
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4
Q

FACTORES DE RIESGO

ENF CROHN

A
  • Asociacion genetica **HLA - A2 y el gen NOD 2 /CARS15 (cromosoma 16)
  • TABAQUISMO**
  • estrogenos puros
  • azucar refinada e hipersensibilidad a la leche de vaca
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5
Q

Asociacion con anticuerpos

CROHN

A

**Ac anti Saccharomyces cerevisiae (ASCA)

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6
Q

PICOS DE INCICIDENCIA

CROHN

A
  • 15 - 25 AÑOS
  • 55 - 65 AÑOS
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7
Q

PREDIMINO DE SEXO

CHRON

A

HOMBRES

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8
Q

CLINCA

CRHON

A
  • DOLOR ABDOMINAL FID
  • DIARREA > 6 SEMANAS (esteatorrea y mucosanginolento)
  • PERDIDA DE PESO
  • FIEBRE
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9
Q

MANIFESTACIONES EXTRAINTESITNALES 30%

CHRON

A
  • ERITEMA NODOSO
  • ESTOMATITIS (AFTAS BUCALES)
  • ARTRITIS
  • UVEITIS
  • LITIASIS RENAL
  • COLELITIASIS
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10
Q

40 - 80% tienen como origen una

pregurna dificil 2022

CHRON

A

FISTULA PERIANAL

puede encontrarse otra patologia perianal

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11
Q

HALLAZGO ENDOSCOPICO caracteritisco

CHRON

A

Afeccion SEGMENTARIA (parches) y discontinua, ulceras aftoides, fisuras, fistulas o estenosis

PATRÓN TIPICO DE EMPEDRADO

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12
Q

HALLAZGO HISTOLOGICO

CHRON

A

INFLAMACION PROFUNDA (TRANSMURAL) GRANULOMAS NO ASEIFICANTES invaden lamina propia por agregados linfoides y macrofagos

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13
Q

QUE INDICA LA PROCALCITONIMA FECAL

CHRON

A

INFLAMACION INTESTINAL

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14
Q

IMAGEN CARACTERITICA EN RX

CHRON

A

MANGUERA DE JARDIN

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15
Q

COMPLIACIONES

CROHN

A
  • OBSTRUCCION INTESTINAL
  • FISTULAS
  • ERITEMA NODOSO
  • AFTAS
  • CALCULOS DE OXALATO
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16
Q

GABINETE DE IMAGEN

CROHN

A

ILEOCOLONOSCOPIA Y ENDOSCOPIA ALTA

17
Q

FUNCIONALIDAD DEL INDICE DE BRADSHAW

CHRON

A

VALORSA LA ACTIVIDAD DE LA ENFERMEDAD

18
Q

FUNCIONALIDAD DE LOS CRITERIOS DE LENNARD JONES

CHRON

A

VALORA SI HAY ENFERMEDAD

19
Q

TX DE ELECCION PARA LA INDUCCION A LA REMISION

CHRON

A

ESTEROIDES (budesonida 9mg/dia)