16-5: Blood Groups Flashcards
The surfaces of ___ carry genetically determined antigen proteins called ___.
RBCs; agglutinogens
ABO Blood Groups
Based on 2 surface proteins (agglutinogen A and B), creating 4 blood types.
Type A blood types have ___ antigens
Type B blood types have ___ antigens
Type AB blood types have ___ antigens
Type O blood types have ___ antigens
A; B; A and B; no
Blood plasma contains ___ that attack any agglutinogens ____.
agglutinins (preformed antibodies); not on their own TBCs
Type A blood types have ___ antibodies
Type B blood types have ___ antibodies
Type AB blood types have ____ antibodies
Type O blood types have ___ antibodies
anti-B; anti-A; no; anti-B and anti-A
Agglutination
transfusion reaction - when the wrong type of blood is given to someone in a transfuciton, the donated RBCs are attacked by the recipient’s plasma antibodies, causing the blood cells to clump (agglutinate) and become lodged in capillaries
During agglutination, the RBCs ___ within a few hours
undergo hemolysis
What are symptoms of an agglutination?
chills, fever, nausea, vomitting, low BP leading to shock
What is the treatment for an agglutination?
diuretics and push fluid, flushing out Hg to prevent kidney damaged
Agglutination may eventually lead to ___.
kidneys shutting down, becoming seriously damaged, or death
In a transfusion, we are interested in the interaction between the donor’s ___ and the recipient’s ___.
donor’s antigens on RBCs and recipients antibodies in plasma
Type A can donate to ___
A or AB
Type B can donate to ___
B or AB
Type AB can donate to ___
AB
Type O can donate to
A, B, AB, or O
