#152 Emergency Contraception Flashcards
What type of emergency contraception is available over the counter?
Progestin-only pill, which consists of 1.5mg of levonorgestrel
For how long after unprotected sex is levonorgestrel use for emergency contraception recommended?
Up to 72 hours, but best as soon as possible
What is the mechanism of action of ulipristal acetate?
Selective progesterone receptor modulator, or antiprogestin
What is the dose of ulipristal acetate?
30mg
For how long after unprotected sex is ulipristal acetate use for emergency contraception recommended?
Up to 120 hours
What regimens are approved by FDA for emergency contraception? And which are not?
Ulipristal acetate and levonorgestrel pill are FDA approved. Combined progestin-estrogen pills and copper IUD are not FDA approved
For how long after unprotected sex is a copper IUD useful for emergency contraception recommended?
Highly effective if placed within 5 days, some studies used it as many as 10 days later.
Levonorgestrel-containing IUDs are currently being investigated
How does ulipristal acetate work as an emergency contraception?
Inhibit or delay ovulation. Inhibits follicular rupture even after level of LH has started to increase
How does the levonorgestrel-only regimen work as an emergency contraception?
Inhibit or delay ovulation. Delays follicular development when administered before level of LH increases.
Does emergency contraception prevent implantation of a fertilized egg?
Unlikely
How does the copper IUD function as an emergency contraception?
Prevents fertilization by affecting sperm viability and function. May also affect the oocyte and endometrium.
Does emergency contraception confer risk to an established pregnancy or harm to developing embryo?
No, based off studies of teratogenic risk of contraception during daily use of oral contraceptives
Have any deaths or serious complications been linked to use of emergency contraceptive pills?
No
What are short-term adverse effects of emergency contraceptive use?
Nausea, headache, irregular bleeding, breast tenderness, abdominal pain, dizziness, and fatigue
What bleeding irregularities are common with emergency contraceptive use?
Menstrual period usually occurs within 1 week of expected time. Some will have irregular bleeding or spotting in the week or month after treatment. If taken earlier in the cycle will likely experience bleeding before expected menses.