15. Principles of Tendon Healing Flashcards
what are the 3 vascular sources to a tendon?
- musculotendinous junction
- bone/periosteum interface
- paratenon by way of hilus **majority of supply
what are the phases of tendon healing?
- impact
- inflammatory
- proliferative
- remodeling
when does bridging of the gap occur?
week 2 (10-14 days)
what tendons are active in the swing phase of gait cycle?
tibialis anterior
EHL
EDL
peroneus tertius
how long does it take for an in-phase tendon transfer to regain activity? vs. out-of phase?
in phase: 7-8 wks
out of phase: 1-2 yrs
Describe the building blocks of tendon anatomy.
tropocollagen –> collagen filament –> fibrils –> fiber –> fasicle
what does an endotenon surround?
envelopes a group of fasicles
what does an epitenon surround?
the tendon
what is a mesotenon?
epitenon + paratenon
what is a paratenon?
continuous with the epitenon, contains nerve and blood vessels
what is the difference btwn paratenon and tendon sheath?
tendon sheaths are found in tendons that change direction
paratenon is found in tendons w/ straight pull aka achilles tendon
what is a hilus?
point of attachment of mesotenon to tendon to provide bloodflow
what is plicae?
CT doubled over on itself to provide free pistoning motion of the tendon, stretching and folding to protect the vital mesotenon from excessive tesnion
What happens on a cellular level in the impact phase of tendon healing?
- complement cascade is activated
- vasoconstriction
- platelet aggregation
- chemotaxis
What is the timescale for inflammatory phase?
48-72 hours
days 2-3
What happens on a cellular level in the inflammatory phase of tendon healing?
- cellular infiltration: PMN, macrophage
- jelly-like serous and granulation tissue at gap zone
- acidic environment (low O2 tension) stimulates fibroblast and collagen production
what is the time scale of proliferative phase of tendon healing?
5 days
what occurs in the proliferative phase of tendon healing?
- fibroblasts bridge gap zone
- collagen synthesis
- return of function
What is the timescale for remodeling phase?
15-28 days