15 - Laboratory Techniques in Immunology Flashcards
1
Q
When do you expect to find excess antigen in a patient with infectious disease?
A
Early infection
2
Q
What is a window period?
A
All available antigen complexed with antibody ▶️ equivalence
*neither free Ag nor free Ab can be detected in patient serum
3
Q
When do you expect to find an antibody excess in a patient with a infectious disease?
A
Late in infection
4
Q
What does the direct fluorescent antibody test detect?
A
Identifies or localize Ag in a tissue
5
Q
What does the indirect fluorescent antibody test detect?
A
Detects pathogen-specific Ab
6
Q
What is the usage of the direct Coombs?
A
Detect infants at risk to develop erythroblastosis fetalis
*detect RBC of the infant with anti-Rh(+) from mother already bound to them
