15 DRUGS OF ABUSE

Question 1

Define withdrawal syndrome

Answer 1

Evidence of physical dependance caused by removal of the drug- generally results in the opposite to the drug effect

Question 2

Define physical dependance

Answer 2

Develops as a result of tolerance and is characterised by withdrawal syndrome

Question 3

Define tolerance

Answer 3

Receptor down regulation, reduced receptor sensitivity, increased compensatory mechanism

Question 4

Define substance related syndrome

Answer 4

Continued drug use despite substance related problems, tolerance and withdrawal syndrome. If you have 1 or 2 drug abuse, 3 addiction.

Question 5

Describe some symptoms of opioid withdrawal

Answer 5

Craving, restlessness, irritability, hypersensitivity to pain, nausea, muscle aches, hallucinations, anxiety, maybe autonomic dysfunction sweating, tachycardia, vomiting, diarrhoea, fever