1401 to 1500 Flashcards
- A 22yo Greek man presents with rapid anemia and jaundice following tx of malaria. He is noted to have Heinx bodies. Choose the single most likely cause from the given options? a. G6PD deficiency b. Anemia of chronic disease c. Pernicious anemia d. IDA e. Vit B12 deficiency
Ans. The key is A. G6PD deficiency. [G6PD (glucose-6-phosphate dehydrogenase) deficiency exacerbated by administration of oxidant drugs (e.g., primaquine, dapsone, quinidine) can also result in Heinz bodies].
- A 65yo has terminal cancer and his pain is relieved by a fentanyl patch but he now complains of shooting pain in his arm. Which of the following will add to his pain relief? a. Gabapentin b. Radiotherapy c. Amitryptiline d. Morphine
Ans. The key is A. Gabapentin. [Shooting in the arm indicates neuropathic pain for which both amytriptiline and gabapentin can be used].
- A 45yo male alcoholic presents after a large hematemesis. He has some spider naevi on his chest, BP=100/76mmHg, pulse=110bpm. He has a swollen abdomen with shifting dullness. a. Gastric ca b. Mallory-weiss tear c. Esophageal ca d. Esophageal varices e. Esophagitis f. Peptic ulceration
Ans. The key is D. Esophgeal varices. [Spider nevi and ascites suggest advanced liver disease. Here in alcoholic middle aged man having large hematemesis with above mentioned features are very suggestive of bleeding from esophageal varices secondary to portal hypertension in liver cirrhosis].
- A 23yo woman presents with a 1cm small smooth, firm, mobile mass in her left breast. She is very anxious. What is the most appropriate inv? a. Mammography b. US breast c. FNAC d. Mammography and US
Ans. The key is B. US breast. [This is fibroadenoma of the breast (breast mouse) for which US of breast is the appropriate investigation and if it reveal a fibrous lump we shall go for FNAC. Another point a doctor should know that for any suspicious breast lesion radiology should must be done before options of biopsy and investigation of choice in radiology is US scan before the age of 35 and mamm
- A pt was admitted with abdominal pain, diarrhea, pigmented palmar creases and buccal mucosa. What is the most probable dx? a. Addison’s disease b. Cushing syndrome c. Pheochromocytoma d. Hyperthyroidism e. Hypoparathyroidism
Ans. The key is A. Addison’s disease. [Abdominal pain, diarrhea, pigmented palmar creases and buccal mucosa are well known features of addisons disease].
- A 36yo pt came with diarrhea, bleeding, weight loss and fistula. What is the single most likely dx? a. Colorectal ca b. Celiac disease c. CD d. UC e. IBS
Ans. The key is C. CD. [Bloody diarrhea can occur in both CD & UC. Also weight loss is common! but fistula formation is unique feature of CD].
- A 45yo man has undergone detox and now wants a drug to stop him from craving alcohol. What med would be that drug of choice? a. Disulfiram b. Acamprosate c. Thiamine d. Naloxone e. Diazepam
Ans. The key is B. Acamprosate. [Disulfirum is a deterrent which does not reduce craving. Acramposate by restoring deranged brain chemical reduces craving].
- A 68yo man awoke to find that he is unable to close his left eye and dribbling saliva from the left angle of his mouth. What is the single most appropriate option? a. Facial nerve b. Glossopharyngeal nerve c. Hypoglossal nerve d. Optic nerve e. Vagus nerve
Ans. The key is A. Facial nerve. [Features are suggestive of left sided facial nerve palsy].
- A 19yo female dx with trichomonas vaginalis. LMP was 10d ago. What is the best antibiotic tx? a. Erythromycin b. Vancomycin c. Metronidazole d. Penicillin e. Clarithromycin f. Doxycycline g. Fluconazole h. Clotrimazole
Ans. The key is C. Metronidazole.
- A 35yo man has been given a dx of allergic rhinitis and asthma. Exam: peripheral neuropathy with tingling and numbness in a ‘glove and stocking’ distribution. Skin elsions are present in the form of tender subcutaneous nodules. The pt is responding well to corticosteroids. What is the single most appropriate dx? a. AS b. Churg-strauss syndrome c. Crytogenic organizing d. Extrinsic allergic a
Ans. The key is B. Churg-strauss syndrome. [The American College of Rheumatology has identified six criteria for the diagnosis of CSS:[3] • Asthma (wheezing, expiratory rhonchi). • Eosinophilia of more than 10% in peripheral blood. • Paranasal sinusitis. • Pulmonary infiltrates (may be transient). • Histological confirmation of vasculitis with extravascular eosinophils. • Mononeuritis multiplex or
- A 28yo woman comes with sudden onset vomiting and pain per abdomen. Exam: mobile swelling in the right iliac fossa. What is the most probable dx? a. Ectopic pregnancy b. Tubo-ovarian abscess c. Acute appendicitis d. Ovarian torsion e. Diverticulitis
Ans. The key is D. [As there is no history of amenorrhea ectopic pregnancy is less likely. So dx is possible ovarian torsion].
- A 68yo man on tx for an irregular heart beat comes to the ED. He has palpitations for the last 3h. Exam: pulse=regular, 154bpm. Carotid sinus massage settled his pulse down to 80bpm. What is the most likely rhythm disturbance? a. SVT b. V-fib c. VT d. V-ectopics e. A-fib
Ans. The key is A. SVT. [Regular tachycardia responding to vagal maneuver is likely SVT].
- A 43yo man with a hx of hospital admissions talk about various topics, moving from one loosely connected topic to another. What is the most likely dx? a. Psychosis b. Mania c. Schizophrenia d. Pressured speech e. Verbal diarrhea
Ans. The key is B. Mania. [Flight of idea is common in mania].
- An 18yo girl presents with rash on her trunk, abdominal pain, arthritis, proteinuria and hematuria. What is the most probable dx? a. TTP b. ITP c. HSP d. HUS e. Measles
Ans. The key is C. HSP. [Henoch-Schönlein purpura (HSP) is an acute immunoglobulin A (IgA)–mediated disorder characterized by a generalized vasculitis involving the small vessels of the skin, the gastrointestinal (GI) tract, the kidneys, the joints, and, rarely, the lungs and the central nervous system (CNS). Rash on trunk, abdominal pain, arthritis, proteinuria and hematuria are well known featur
- A pt is on loop diuretics. What effect do loop diuretics produce? a. Low Na+, low K+ b. Low Na+, normal K+ c. Normal Na+, normal K+ d. High Na+, low K+ e. High Na+, high K+
Ans. The key is A. Low Na+, Low K+. [Loop diuretics causes hyponatremia and hypokalemia].
- A 6yo girl is being investigated for renal failure. She is found to have a congenital abnormality of the insertion of the ureters into the urinary bladder. What is the single most likely cause for renal failure in this pt? a. SLE b. PKD c. Wilm’s tumor d. Acute tubular necrosis e. Reflux nephropathy
Ans. The key is E. Reflux nephropathy. [Reflux nephropathy is kidney damage (nephropathy) due to urine flowing backward (reflux) from the bladder toward the kidneys; the latter is called vesicoureteral reflux (VUR)].
- A 76yo man is in the CCU 2d after an acute MI. He tells you that he had an episode of rapid pounding in the chest lasting for about 2mins. He remains conscious throughout. What is the most likely rhythm? a. SVT b. VF c. VT d. V-ectopics e. A-fib
Ans. The key is C. VT. It is wrong key. Correct key should be D. V-ectopics.
- A 49yo man comes with hx of cough and SOB. His CD4 count is measured as 350. CXR shows lobar consolidation. What is the single most appropriate option? a. Mycobacterium avium intercellular b. CMV c. Streptococcus d. Toxoplasmosis e. Pneumocystis jerovici
Ans. The key is C. Streptococcus. [Features are consistent with lobar pneumonia].
- A 32yo woman with prv hx of PID now presents with severe abdominal pain. Her LMP was 8wks ago. What is the most probable dx? a. Ectopic pregnancy b. Ovarian torsion c. Hematometrium d. Chronic PID e. Cholecystitis
Ans. The key is A. Ectopic pregnancy. [PID is a risk factor for ectopic pregnancy].
- A 25yo who is 38wks pregnant presents to the labour ward with a hx of fewer fetal movements than usual during the evening. She also says that abdominal contractions are coming every few minutes and she is having a blood stained show per vagina for the last few minutes. Exam: cervix is fully affaced, 9cm dilated, cephalic presentation and station is +1. Choose the single most likely dx? a. AP
Ans. The key is C. Labour. [Abdominal contractions coming every few minutes, having blood stained show per vagina, fully effaced cervix with dilatation of 9 cm, cephalic presentation and station +1 suggests that the patient is in labour].
- A 30yo woman has a painless lump in the outer aspect of her left breast. She has had a prv breast lump. Her grandmother had breast cancer at 70yrs. She has a 1cm smooth, firm, discrete, mobile lump in the other quadrant region of the left breast. What is the single most likely dx? a. Breast abscess b. Breast carcinoma c. Breast cyst d. Fibro-adenoma e. Sebaceous cyst
Ans. D. Fibroadenoma. [H/O previous brest lump and presently with a lump of 1 cm size which is smooth, firm (not hard), discrete and mobile (not fixed) suggests fibro-adenoma].
- A 38yo woman is in the ED following an OD of her meds. She doesn’t need med tx for the OD. She says she wishes to be discharged. What is the single most appropriate management? a. Community psychiatric nurse visit b. Psychiatric OPD review the next day c. Prescribe anti-depressants d. Admission under the mental health act e. Discharge and allow to go home
Ans. The key is D. Admission under the mental health act. [There is every chance of repeat over dose. So she should be admitted under mental health act].
- A 63yo male presents after having had a seizure. Exam: alert and oriented. Exam: inattention on the left side and hyperreflexia of the arm. What is the most probable dx? a. Cerebral tumor b. Pituitary adenoma c. Cerebellar abscess d. Huntington’s chorea e. Parkinsonism
Ans. The key is A. Cerebral tumour.
- A 70yo lady on Raloxifene for osteoporosis has recently to the UK from Australia. She now presents with severe chest pain, SOB and suddenly collapsed in the ED. What is the single most appropriate dx? a. MI b. Aortic dissection c. Pulmonary embolism d. Costochondritis e. Pneumothorax
Ans. The key is C. Pulmonary embolism. [Prolonged air travel is a risk factor for pulmonary embolism].
- A 35yo woman complains of hoarseness of voice 3h after partial thyroidectomy. She had no hx of phonation probs before the surgery. What is the single most appropriate inv? a. Laryngoscopy b. Bronchoscopy c. CT neck d. CXR e. Barium swallow
Ans. The key is A. Laryngoscopy. [Probable diagnosis is recurrent laryngeal nerve palsy].
- A 40yo pt came to OPD with complaint of fever, pleuritic chest pain, productive cough and painful vesicles around the lips. Exam: temp=38C. He has a hx of splenectomy last yr. What is the single most likely causative organism? a. Pneumococcal pneumonia b. Staphylococcus c. Klebsiella d. Streptococcus e. Chlamydia psitacci
Ans. The key is A. Pneumococcal pneumonia. [painful vesicles around the lips is well known association of pneumococcal pneumonia. Also pleuritic chest pain and productive cough are present in pneumococcal pneumonia].
- A 37yo male pt who recently returned back to UK from UAE attends the OPD with complaint of dry cough, breathlessness and anorexia. According to him he had flu like symptoms a week ago. He is slightly confused. Inv: lymphopenia & decreased Na+. CXR: bi-basal consolidation. What is the single most likely causative organism? a. Legionella b. Chlamydia pneumonia c. PCP d. Viral pneumonia e. Chla
Ans. The key is A. Legionella. [H/O travel (staying in AC and watersystem of hotel), lymphopenia, decreased Na+, bi-basal consolidation are well known features of legionnaires disease].
- A 20yo student came to the OPD with complains of headache, malaise, dry cough, joint pain and vomiting. Exam: temp=39C. CXR: patchy consolidation. What is the single most likely causative organism? a. Pneumococcal pneumonia b. Mycoplasma c. Klebsiella d. Streptococcus e. PCP
Ans. The key is B. Mycoplasma.
- A 45yo man presented to his GP with vague symptoms of headache, proximal muscle weakness and nocturia. Test results show him to be severely HTN (230/130mmHg) and hypokalemic. What is the most probable dx? a. Addison’s disease b. Conn’s disease c. Familial hyperaldosteronism d. Cushing’s disease e. Cushing’s syndrome
Ans. The key is B. Conn’s disease. [High BP is often the only presentation of Conn’s syndrome. Loss of K+ in urine leads to hypokalemia which in turn causes muscle weakness and polyuria particularly nocturia].
- A man says his insides are rotting and nobody has buried him. Which term best describes his condition? a. Delusion of nihilism b. Delusion of guilt c. Delusion of persecution d. Incongruent affect e. Clang association
Ans. The key is A. Delusion of nihilism.
- A man with chronic cough presents with copious purulent sputum. What is the single most dx? a. Bronchitis b. Bronchiectasis c. COPD d. Pneumonia e. Emphysema
Ans. The key is B. Bronchiectasis.
- A 32yo man working in a shipyard comes with SOB. Exam: dullness on left side of the chest, pain in left side of chest, pleuritic rub and crackles been heard on the same side. What is the single most likely dx? a. Pericarditis b. Pleurisy c. Pleural effusion d. CCF e. TB
Ans. The key is C. Pleural effusion. [Shipyard worker are exposed to asbestos and presenting case has developed mesothelioma causing pleura thickening and pleural effusion. Though it is usual that in pleural effusion pleural rub reduces or becomes absent but it is also possible to get pleural rub even in pleural effusion and the like diagnosis is pleural effusion here].
- A 67yo female presents with balance prbs. Exam: nystagmus on left lateral gaze, a loss of the left corneal reflex and reduced hearing in the left ear. What is the most likely dx? a. Meniere’s disease b. Acoustic neuroma c. Cerebral abscess d. Pituitary tumor e. Gentamicin
Ans. The key is B. Acoustic neuroma. [nystagmus, loss of corneal reflex, hearing loss, balance problem are well known feature of acoustic neuroma].
- A 22yo man reports a 2d hx of hoarseness of voice. He denies any weight loss but he has been smoking for 4yrs. What is the single most appropriate inv? a. None b. Laryngoscopy c. Bronchoscopy d. BAL e. CXR
Ans. The key is B. Laryngoscopy. It is a wrong key! Correct key is A. None. [If horseness is of >3 weeks in man >50 yrs and smoker and heavy drinker to rule out cancer do CXR and\or laryngoscopy- NICE guideline].
- A 34yo IVDA (intravenous drug addict) presents with a 4m hx of productive cough. He has lost 10kgs. What is the single most appropriate inv? a. Sputum for AFB b. Laryngoscopy c. Bronchoscopy d. CT neck e. CXR
Ans. The key is A. Sputum for AFB. [In IVDA immunity becomes low and easily gets infected with TB].
- A 25yo pt came to the OPD with complaint of fever, malaise, breathlessness, cough and anorexia. His gf has got similar symptoms. He had hx of sore throat and ear discharge a month ago. What is the single most likely causative organism? a. Legionella b. Mycoplasma c. Chlamydia pneumonia d. PCP e. Chlamydia psitacci
Ans. The key is C. Chlamydia pneumonia.
- A 72yo male presents with acute confusion. He has been in the hosp for 2wks having been treated for a DVT. The nurses have noticed that he became increasingly drowsy. Exam: small scalp laceration, a GCS of 8 and bilateral up-going plantar response. a. Infection toxicity b. Delirium tremens c. Extradural hematoma d. Subdural hematoma e. Electrolyte imbalance
Ans. The key is D. Subdural hematoma. [Even trivial head trauma can lead to subdural hematoma. Presence of small scalp laceration, confusion and becoming increasingly drowsy Glasgow coma scale of 8 are suggestive of subdural hematoma].
- A 50yo DM pt came to the OPD with complaint of fever, muscle ache, dry cough and anorexia. Inv: CXR=upper lobe cavitation. What is the single most likely causative organism? a. Legionella b. Mycoplasma c. Staphylococcus d. Klebsiella e. Streptococcus
Ans. The key is D. Klebsiella. [Upper lobe cavitation favours Klebsiella pneumonia. Also it is well known that staphylococcal and klebsiella pneumonia are more common in DM than normal person].
- A 20yo man complains that all his movements are being watched. Sometimes he feels as though his actions are being controlled by his radio. At other times he is aware of voices describing what he is doing. What is the most probable dx? a. Mania b. Drug induced psychosis c. Delusion of control d. Schizophrenia e. Korsakoff psychosis
Ans. The key is D. Schizophrenia.
- A 35yo is agitated and euphoric. He claims to be helping the prime minister with economic policy, although this is not true when checked. What is the most likely dx? a. Mania b. Schizophrenia c. Hypomania d. Drug induced personality disorder e. Delusion of grandeur
Ans. The key is E. Delusion of grandeur. Key is wrong! Correct key should be mania. [Agitated, euphoric and delusion of grandiosity makes the likely dx to be “Mania”. Agitation and euphoria are not feature of delusion of grandiosity but mania].