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Thera XI > 14 Study Guide > Flashcards

14 Study Guide Flashcards

1
Q

Which compounds have dipole dipole reactions?

A

Alcohol, Ketone, etc.

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2
Q

Which compounds have dipole dipole reactions?

A

Alcohol, Ketone, etc.

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3
Q

What are some common infusion related ADRs of IVIG?

A

HA and Arthralgia as well as possible renal toxicity

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4
Q

What would be a better choice between Morphine CR and Hydromorphone in a patient that requires acute pain control?

A

Hydromorphone b/c it has quicker onset relative to controlled release

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5
Q

Iron has the best absorption with?

A

Ascorbic acid

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6
Q

What do you take for iron toxicity?

A

Deferoxamine

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7
Q

What is the DDI with Sulfa and Omeprazole?

A

No DDI with these two agents

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8
Q

What are the targeted Phenytoin Levels?

A

10-20mcg/L

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9
Q

What factors are derived from plasma?

A

Plasma, IVIG, Alpha-something ase, Factor IX

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10
Q

Which benzos have no CYP metabolism?

A

LOT: Lorazepam, Oxazepam, Temazepam. Glucuronidation only, good for elderly

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11
Q

Which statins have the most CYP?

A

SAL: Simvastatin, Atorvastatin, Lovastatin

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12
Q

Which statins have the fewest CYP interaction?

A

Pravastatin, Rosuvastatin, Fluvastatin

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13
Q

Which analgesic requires CYP for activation?

A

Codeine (2D6 to morphine)

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14
Q

Where would you look up a generic name that your pharmacy doesn’t have?

A

Red Book

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15
Q

Which drug indicates that a patient needs pneumococcal vaccine?

A

Digoxin

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16
Q

What medication for constipation is most low acting?

A

Psyllium

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17
Q

What do you give for gout attack?

A

NSAID first line

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18
Q

What is a serious ADR of Xolair?

A

Anaphylaxis

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19
Q

What should be remembered about Medrol dose pack?

A

Take with food and may cause insomnia

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20
Q

What are some short acting steroids?

A

Hydrocortisone/Cortisone

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21
Q

What are some intermediate acting steroids?

A

Methylprednisone, Prenisolone, Prednisone

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22
Q

What are some long acting steroids?

A

Beta/dexamethasone

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23
Q

What is the correct dose for prednisone for acute asthma exacerbation?

A

40mg daily for 6 days

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24
Q

What is a DM medication that is used to decrease post-prandial glucose?

A

Sulfonylureas, Meglitinides

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25
Q

What can an alcoholic take that could potentially protect her liver?

A

Milk thistle

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26
Q

When is a patient with COPD a candidate for empiric Abx treatment?

A

Increased sputum purulence, Increased sputum volume, Dyspnea

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27
Q

What is TACE as it relates to TNF and IL-1?

A

Binding to soluble TNF

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28
Q

An 8 year old boy is prescribed prednisone 20mg PO QD #100. What would you counsel his parent about?

A

Don’t d/c w/o consulting MD first. This medication can cause growth suppression

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29
Q

Which BBs are approved for CHF?

A

Coreg and Metoprolol Succinate

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30
Q

What is normal Prothrombin Time?

A

10-13 seconds

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31
Q

What is the time window to use antiplatelet drugs for stroke?

A

3 hours (up to 4.5h for certain circumstances)

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32
Q

What are the different LDL goals, considering CVD?

A

< 100 if no over CVD. < 70 if overt CVD

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33
Q

If you’re trying to target TGs for a patient before anything else, what are the best agents to use?

A

Fibrates! Niacin is a second line agent

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34
Q

What factors can decrease INR?

A

St. Johns Wort. CoQ10. Ginseng. Green tea

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35
Q

What factors can increase INR?

A

Fish oil. Garlic. Ginger. Gingko. Vitamin E

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36
Q

What are the GPIIb/IIIa inhibitors?

A

TEA: Tirofiban. Eptifibitide. Abciximab

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37
Q

Patient needs a diuretic but has had SJS in the past, what would you give?

A

Ethacrynic acid

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38
Q

When are ACE-I/ARBs CI?

A

3rd trimester pregnancy

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39
Q

Patient needs HTN med that increases K level?

A

Spironolactone

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40
Q

CCB that decreases HR?

A

Verapamil and Diltiazem

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41
Q

What are the effects of Hypothyroidism on coumadin?

A

Hypothyroidism will cause a delayed response to coumadin d/t the slow metabolism of clotting factors by the liver

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42
Q

Zometa (Zolindronic acid) for osteoporosis, whats the dose?

A

5mg IV Q yearly

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43
Q

How would you know if patient has Folic Acid deficiency anemia?

A

High MCV. B12 is normal

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44
Q

Which DM medications have BBWs?

A

Metformin (lactic acidosis). Pioglitazone (cause or exacebate CHF)

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45
Q

What what A1c do you initiate dual therapy?

A

7.5-9

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46
Q

Physician orders a 10U IV bolus, what type of insulin do you give?

A

Only R insulin can be given as bolus

47
Q

Which insulin is most like endogenous insulin?

A

Glargine or Lantus

48
Q

What are the birth control pills starting/back up requirements?

A

Sunday start: back up for 7 days. Start on first day of bleeding, no backup necessary

49
Q

What is used for HPA axis suppression?

A

Prednisone daily for long term

50
Q

What can be used OTC for menopause?

A

Black cohosh

51
Q

A patient has adrenal insufficiency d/t a tumor, what should be given?

A

Testosterone. Aldosterone

52
Q

What is best to decrease postprandial glucose level?

A

Forgot to type it in… Whoops

53
Q

Antibiotic coverage for atypical microbes?

A

Doxycycline and Clarithromycin

54
Q

Patient with foot debridement, Abx?

A

Cefotetan

55
Q

Other than Strep pneumo, what organism causes CAP in otherwise healthy individuals?

A

Mycoplasma

56
Q

What drugs cause urine discoloration?

A

Phynazopyridine. Nitrofurantoin. Rifampin

57
Q

Which drug for overactive bladder is available in a patch?

A

Oxybutynin

58
Q

Elderly needs antihistamine for sleep, what would you give?

A

Loratidine

59
Q

What are some common infusion related ADRs of IVIG?

A

HA and Arthralgia as well as possible renal toxicity

60
Q

What would be a better choice between Morphine CR and Hydromorphone in a patient that requires acute pain control?

A

Hydromorphone b/c it has quicker onset relative to controlled release

61
Q

Iron has the best absorption with?

A

Ascorbic acid

62
Q

What do you take for iron toxicity?

A

Deferoxamine

63
Q

What is the DDI with Sulfa and Omeprazole?

A

No DDI with these two agents

64
Q

What are the targeted Phenytoin Levels?

A

10-20mcg/L

65
Q

What factors are derived from plasma?

A

Plasma, IVIG, Alpha-something ase, Factor IX

66
Q

Which benzos have no CYP metabolism?

A

LOT: Lorazepam, Oxazepam, Temazepam. Glucuronidation only, good for elderly

67
Q

Which statins have the most CYP?

A

SAL: Simvastatin, Atorvastatin, Lovastatin

68
Q

Which statins have the fewest CYP interaction?

A

Pravastatin, Rosuvastatin, Fluvastatin

69
Q

Which analgesic requires CYP for activation?

A

Codeine (2D6 to morphine)

70
Q

Where would you look up a generic name that your pharmacy doesn’t have?

A

Red Book

71
Q

Which drug indicates that a patient needs pneumococcal vaccine?

A

Digoxin

72
Q

What medication for constipation is most low acting?

A

Psyllium

73
Q

What do you give for gout attack?

A

NSAID first line

74
Q

What is a serious ADR of Xolair?

A

Anaphylaxis

75
Q

What should be remembered about Medrol dose pack?

A

Take with food and may cause insomnia

76
Q

What are some short acting steroids?

A

Hydrocortisone/Cortisone

77
Q

What are some intermediate acting steroids?

A

Methylprednisone, Prenisolone, Prednisone

78
Q

What are some long acting steroids?

A

Beta/dexamethasone

79
Q

What is the correct dose for prednisone for acute asthma exacerbation?

A

40mg daily for 6 days

80
Q

What is a DM medication that is used to decrease post-prandial glucose?

A

Sulfonylureas, Meglitinides

81
Q

What can an alcoholic take that could potentially protect her liver?

A

Milk thistle

82
Q

When is a patient with COPD a candidate for empiric Abx treatment?

A

Increased sputum purulence, Increased sputum volume, Dyspnea

83
Q

What is TACE as it relates to TNF and IL-1?

A

Binding to soluble TNF

84
Q

An 8 year old boy is prescribed prednisone 20mg PO QD #100. What would you counsel his parent about?

A

Don’t d/c w/o consulting MD first. This medication can cause growth suppression

85
Q

Which BBs are approved for CHF?

A

Coreg and Metoprolol Succinate

86
Q

What is normal Prothrombin Time?

A

10-13 seconds

87
Q

What is the time window to use antiplatelet drugs for stroke?

A

3 hours (up to 4.5h for certain circumstances)

88
Q

What are the different LDL goals, considering CVD?

A

< 100 if no over CVD. < 70 if overt CVD

89
Q

If you’re trying to target TGs for a patient before anything else, what are the best agents to use?

A

Fibrates! Niacin is a second line agent

90
Q

What factors can decrease INR?

A

St. Johns Wort. CoQ10. Ginseng. Green tea

91
Q

What factors can increase INR?

A

Fish oil. Garlic. Ginger. Gingko. Vitamin E

92
Q

What are the GPIIb/IIIa inhibitors?

A

TEA: Tirofiban. Eptifibitide. Abciximab

93
Q

Patient needs a diuretic but has had SJS in the past, what would you give?

A

Ethacrynic acid

94
Q

When are ACE-I/ARBs CI?

A

3rd trimester pregnancy

95
Q

Patient needs HTN med that increases K level?

A

Spironolactone

96
Q

CCB that decreases HR?

A

Verapamil and Diltiazem

97
Q

What are the effects of Hypothyroidism on coumadin?

A

Hypothyroidism will cause a delayed response to coumadin d/t the slow metabolism of clotting factors by the liver

98
Q

Zometa (Zolindronic acid) for osteoporosis, whats the dose?

A

5mg IV Q yearly

99
Q

How would you know if patient has Folic Acid deficiency anemia?

A

High MCV. B12 is normal

100
Q

Which DM medications have BBWs?

A

Metformin (lactic acidosis). Pioglitazone (cause or exacebate CHF)

101
Q

What what A1c do you initiate dual therapy?

A

7.5-9

102
Q

Physician orders a 10U IV bolus, what type of insulin do you give?

A

Only R insulin can be given as bolus

103
Q

Which insulin is most like endogenous insulin?

A

Glargine or Lantus

104
Q

What are the birth control pills starting/back up requirements?

A

Sunday start: back up for 7 days. Start on first day of bleeding, no backup necessary

105
Q

What is used for HPA axis suppression?

A

Prednisone daily for long term

106
Q

What can be used OTC for menopause?

A

Black cohosh

107
Q

A patient has adrenal insufficiency d/t a tumor, what should be given?

A

Testosterone. Aldosterone

108
Q

What is best to decrease postprandial glucose level?

A

Forgot to type it in… Whoops

109
Q

Antibiotic coverage for atypical microbes?

A

Doxycycline and Clarithromycin

110
Q

Patient with foot debridement, Abx?

A

Cefotetan

111
Q

Other than Strep pneumo, what organism causes CAP in otherwise healthy individuals?

A

Mycoplasma

112
Q

What drugs cause urine discoloration?

A

Phynazopyridine. Nitrofurantoin. Rifampin

113
Q

Which drug for overactive bladder is available in a patch?

A

Oxybutynin

114
Q

Elderly needs antihistamine for sleep, what would you give?

A

Loratidine

Thera XI (16 decks)

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