14. Approach To fatigue and weakness

Question 1

Serum osmolality is closely reuglated in the body kept between 280-290 and maintained by ADH system and thirst mechanims. ADH is released in response to osmotic and non osmotic stimuli … 1) osmotic: from increases in serum osmo detected by osmoreceptors in the ant hypothalamus and 2)?

Answer 1

Non osmotic: from dec in BP or BV detected by arterial baroreceptors

Question 2

Other stimulators of ADH release are baroreceptors, nausea, hypoxia, pain, medication and pregnancy. What occurs when there is decreased serum osmolality?

Answer 2

Suppression of thirst and suppression of ADH release which dilutes the urine