13 Death Dt Natural Causes Flashcards
1
Q
Causes of sudden and unexpected death
A
- always in CVS
- cerebral haemorrhage dt MVA
- subarachnoid haemorrhage dt ruptured berrry aneurysm
- ruptured ectopic pregnancy
- haemoptysis dt PTB
- haematemesis dt rultured esophageal varices
- PE
- ruptured aortic aneurysm
2
Q
Cx in coronary atheroma
A
- ulcerated plaques
- haemorrhage within the plaques
- coronary thrombus
3
Q
Most common sites of coronary stenosis and occlusion
A
- L ant descending coronary artery
- R coronary artery
- L circumflex artery
**almost all infarcts are in left ventricle
4
Q
Causes of MI
A
- coronary atheroma
- polyartheritis of coronary
- coronary embolism
- ostial occlusion by syphilis
- aortic stenosis
5
Q
Process of early MI
A
- oedema and pallor muscle (hours)
- tigroid appearance/yellow and haemorrhagic areas (days)
- myomalacia cordis leading to ruptured infarct (days to weeks)
- gelatinous and greyish (weeks)
- myocardial fibrosis (months)
6
Q
Cx of MI
A
- ruptured heart leading to haemopericardium and cardiac temponade
- mural thrombus in L ventricle
- pericarditis
- myocardial fibrosis in L ventricle (septum and posterior)
- cardiac aneurysm in L ventricle (lateral)
7
Q
Mechanism of CAD
A
- myocardial hypoxia leads to AF and Ventricular fibrillation and cardiac arrest and death
8
Q
How hypertensive heart disease cause MI
A
- concentric hypertrophy of L ventricle
- insufficient supply of blood
- causing MI
500-700g
9
Q
Aortic valve ds
- which type occur in elderly and how it occurs
A
- calcific aortic stenosis usually in elderly
- valve thickened and rigid, fusion of valvular commissures and vegetation on cusps
10
Q
What is cardiomyopathy and most commonly occur in which age
A
Absence of HTN or valvular ds
Usually in young adults
11
Q
Types of cardiomyopathies
A
- congestive
- hypertrophic (interventricular septum)
- obliterative
12
Q
Histology of hypertrophic CM
A
- irregular and large fibres
- nuclear pleomorphism
- criss cross muscle fibres
- interstitial fibrosis
13
Q
Cause and histology of myocarditis
A
- unknown aetiology
- 100 or more inflammatory infiltrates with myocyte necrosis
14
Q
Definition Senile myocardium
Findings
Histology
A
- myocardial degeneration due to senility
- findings: heart is brown and flabby soft. The coronary vessels are torturous
Histology: lipofuscin pigments in nuclei, diffuse fibrosis of myocardium
15
Q
Types of ruptured aortic aneurysm and patho
A
- atheromatous aneurysm: media destruction dt fibrolipid degeneration
- dissecting aneurysm: dt degeneration of aortic media (medianecrosis)
- syphilitic aneurysm