12.4 The Endocrine System Flashcards
What is the primary connection between the nervous system and the endocrine system?
hypothalamic-pituitary axis
What is a hormone?
molecule that is secreted into the bloodstream by an endocrine gland that has its effects upon distant target cells that possess the appropriate receptor
What is an endocrine gland?
ductless gland whose secretory products are picked up by capillaries supplying blood to the region
What are exocrine glands?
glands that secrete their products into the external environment by way of ducts
What is a hormone receptor?
polypeptide that possesses ligand-specific binding site
What is autocrine activity?
signaling molecules that modify the activity of the cell which secreted them
What are the two classes of hormones?
peptide and amino acid derivatives
steroids
What is the structure of peptide/steroid hormones?
hydrophilic/hydrophobic
What is the site of synthesis for peptide/steroid hormones?
rough ER/smooth ER
What is the regulation of release for peptide/steroid hormones?
stored in vesicles until signal for secretion is released/synthesized when needed and used immediately
How are peptide/steroid hormones transported?
free/protein carrier
What is the mechanism of effect for peptide/steroid hormones?
second messengers for modification of enzyme activity/bind to cytoplasmic receptors that regulate transcription
What is the timing of effect for peptide/steroid hormones?
rapid and short lived; slow and long lived
How is the endocrine system generally regulated?
feedback
What are tropic hormones?
hormones that regulate other hormones