12.2 Alleles Can Produce Multiple Phenotypes Flashcards
Mutations
Mutations are stable, inherited changes in the genetic material, leading to new variations in the gene pool (new alleles).
Wild Type
The wild type refers to the allele present in most of the population. Other alleles are considered mutant alleles. In plants or wild animals, if wild-type alleles are present less than 99% of the time, the gene is polymorphic.
Multiple Alleles
Multiple alleles often show a hierarchy of dominance, with many different allele combinations for one trait. This means that traits are generally not based on just two alleles.
Incomplete Dominance
In incomplete dominance, heterozygotes have intermediate phenotypes, showing a blend of the two traits.
Codominance
In codominance, alleles produce phenotypes that are both present in the heterozygote. For example, the ABO blood group system has two codominant alleles: I^A, I^B, and recessive i.
ABO Blood Group System
In the ABO blood group system, individuals with the A group make A antigen and anti-B antibodies, those with the B group make B antigen and anti-A antibodies, AB group individuals make both A and B antigens, and O group individuals have no antigen and anti-AB antibodies.
Pleiotropy
Pleiotropy occurs when one allele has multiple phenotypic effects.
Epistasis
Epistasis refers to the phenotypic expression of one gene being influenced by another gene.
Hierarchy of Dominance
Multiple alleles often exhibit a hierarchy of dominance, where certain alleles are dominant over others in determining the phenotype.
New Alleles in the Gene Pool
Mutations introduce new alleles into the gene pool, contributing to genetic diversity within a population. These new alleles may alter traits and affect the phenotype of individuals.