12. HTN Disorders in Pregnanct Flashcards
What’s the difference between chronic vs. gestational HTN?
- Chronic HTN is present before or recognized during first half of preg.
- Gestational HTN is recognized after 20 weeks gestation
BP Guidelines:
- NL
- Elevated
- Stage 1
- Stage 2
- Hypertensive crisis
- NL: 120/80
- Elevated: 120-129/ less than 80
- Stage 1: 130-139/ 80-89
- Stage 2: at least 140/ at least 90
-
Hypertensive crisis: systolic over 180 and/or diastolic over 120
- No other indications of problems = pt needs to change meds ASAP
- Signs of organ damage = immediate hospitiliation
What is needed for the diagnosis of preeclampsia?
- HTN after 20 weeks gestation
- Proteinuria
- (Edema)
What is eclampsia?
Preclampsia + new onset of seizures
Superimposed preeclampsia/eclampsia
Transposed on chronic HTN
Chronic HTN
- What is important to evaluate?
-
Look for maternal end-organ damage:
- CBC/CMP
- Glucose
- 24 hour urine colletion (or spot urine protein:Cr ratio)
- EKG
- ECG
-
Assess well-being of fetus
- Initial US
- Screening US
- Growth US monthly after 28 weeks
- Antepartum fetal testing between 32-42 weeks
Manage mild chronic HTN (BP less than 160/110) => 5
- Deliver
- 12 weeks => delivery: 81mg of Aspirin daily
- Anti-HTN if threshold value is reached
- Prenatal visits every 2-4 weeks until 34-36 weeks, then weekly after.
- Antepartum fetal monitoring
- Deliver: 39-40 weeks.
Severe HTN (BP >160/110)
Treat HTN? (3)
- Methyldopa
- Labetalol
- Nifedipine
What should be AVOIDED in severe chronic HTN?
Why.
- ACE-I
- Angiotensin-receptor blockers
- ↑ risk of malformations (renal dysgenesis, calvarial hypoplasia, fetal growth restriction)
Management of Severe Chronic HTN.
- Monitor:
- If renal disease,
- Antepartum fetal surveillance (=> ____ )
- Deliver:
- Monitor during PG for change in dose
- Monitor to see if superimposed preeclampsia develops
- If renal disease, 24 hour urine collection/trimester
- Antepartum fetal surveillance
- Growth US ever 3-4 weeks
- NST/biophysical profile test
- Deliver: 38 weeks after gestation.
What is gestational HTN?
- HTN after 20 weeks or within 48-72 hours after delivery and goes away by 12 weeks postpartum
- Without any features of preclampsia
What are 4 sx’s of preeclampsia?
- Scotoma (blind spot)
- Blurred vision
- HA
- Epigastric and/or RUQ pain
What may be seen in the brain, heart, and lungs of patient with preeclampsia?
- Brain = cerebral edema and/or fibrinoid necrosis, thrombosis, microinfarcts and petechial hemorrhages
- Heart = absence of NL intravascular volume expansion (third spacing) and ↓ in circulating blood volume
- Lungs = noncardiogenic pulmonary edema
What ages are more at risk for preeclampsia?
Less than 20 and older than 35.
Which level of proteinuria is associated with mild vs. severe preeclampsia?
-
Mild =
- BP: >140/90 but less than 160/110
- Proteinuria 300 mg => 5g /24-hr urine bg
- or Single urine protein:Cr ratio of 0.3 mg/dL
-
Severe =
- BP: >160/>110 on 2 occsaions 4 hours apart
- Proteinuria of at least 5g /24-hr
- or [3+ protein] on 2 random urine dips, at least 4 hours apart