12 Flashcards

0
Q

Transformation

A

One strain of bacteria (harmless) had apparently been changed permanently into another (the disease causing)

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1
Q

Griffith

A

Bacteria, discovered things

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2
Q

Avery

A

Discovered that the nucleic acid DNA stores and transmits the genetic information from one generation of an organism to the next

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3
Q

Hershey-Chase

A

studied viruses, nonliving particles smaller than a cell that can infect organisms
-discovered radiation in bacteriophage phosphorous-32 in bacterium

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4
Q

Bacteriophage

A

“Bacteria eater” virus that infects bacteria

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5
Q

Genes must do which four things

A
  1. ) carry information from one generation to the next
  2. ) put that information to work by determining the heritable characteristics of organisms
  3. ) genes had to be easily copied
  4. ) capable of mutation
    * dna does this all*
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6
Q

Nucleotides

A

DNA is a long molecule made up of these units

5-carbon sugar, phosphate, nitrogenous base

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7
Q

Purines

A

Have two rings (adenine and guanine)

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8
Q

Pyrimidines

A

One ring- cytosine and thymine

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9
Q

Backbone of DNA

A

Formed by sugar and phosphate

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10
Q

Chargaff’s rules

A

Found that G = C and A= T

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11
Q

Franklin

A

X-Ray diffraction

Showed that DNA stands are twisted around each other and that nitrogenous bases are near the center

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12
Q

Watson and crick

A

Figured out hydrogen bonds and the double helix using franklin’s work

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13
Q

Base pairing

A

Watson and crick found that every base has exactly another; explained chargaff’s rules

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14
Q

Two stands are said to be…

A

Antiparallel (facing opposite directions)

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15
Q

Prokaryotes have DNA in the…

16
Q

Most eukaryotes have as much as___times the amount of DNA as prokaryotes

17
Q

DNA molecule must be folded into a space..

A

Only one thousandth of its length

18
Q

Chromatin

A

Eukaryotic chromosomes contain both DNA and protein, tightly packed together to form chromatin

19
Q

Histones

A

Chromatin consists of DNA tightly coiled around proteins called Histones

20
Q

Nucleoside

A

DNA and Histones molecules together form this headline structure

21
Q

Complementary

A

DNA strands are said to be complementary because each strand of DNA can be used to make the other strand

22
Q

Replication forks

A

The sites where separation and replication occur

23
Q

Replication

A

Copying process that duplicates DNA before a cell divides

24
DNA polymerase
The principal enzyme involved in DNA replication because it joins individual nucleotides to produce a DNA molecule which is a polymer -also proofreads each new DNA strand helping to maximize the odds that each molecule is a perfect copy of the original
25
Semi conservative replication
The form of replication where each double helix contains one old strand acting as a template for the making of a new strand
26
Single stranded DNA binding protein
Stabilizes unwound strand of DNA
27
Topoisomerase
Prevents supercooling
28
Ligase
Replaces RNA bases with DNA "glue" together Okazaki fragments
29
DNA in prokaryotes is generally..
A single circular molecule